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CAS No.: 663598-66-1
Cat No.: BADC-00472
Purity: ≥98%
4.5 
1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid is a disulfide-containing crosslinker or linker building block for redox-responsive bioconjugation and ADC-related linker design. The disulfide bond provides a reduction-sensitive element, while the terminal reactive groups enable attachment to appropriately functionalized biomolecules or small-molecule partners. The molecule uses not clearly defined from product name; verify structure before assigning antibody conjugation chemistry on one side and pyridyl-disulfide / activated disulfide handle for thiol-containing payloads or thiol exchange partners on the other, with disulfide trigger with c5/alkyl spacer segment providing the spacer/cleavable region. Conjugation orientation and reduction sensitivity should be evaluated in the context of the final construct because local substitution and neighboring groups can influence disulfide behavior.
Structure of 663598-66-1
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1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid is a complex chemical compound with potential applications in bioscience and pharmaceutical research. Here are some key applications:
Bioconjugation: This compound can be utilized in bioconjugation techniques to link biomolecules like proteins, peptides, or antibodies. By using its functional groups, it allows for specific and stable attachment to target molecules. This application is essential in the development of targeted drug delivery systems and diagnostic assays.
Protein Labeling: The unique chemical structure of 1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid makes it suitable for labeling proteins with fluorescent or radioactive tags. This facilitates the tracking and quantification of proteins in various biological experiments. Such labeled proteins are vital in research areas like proteomics and molecular biology.
Redox Studies: Due to the presence of the disulfide bond, this compound is ideal for redox biology studies focusing on the function and regulation of redox-active enzymes and pathways. Researchers can use it to investigate redox mechanisms and their role in cellular physiology. Its application can help in understanding oxidative stress and developing antioxidants.
Enzyme Inhibition Studies: This compound has potential use as an enzyme inhibitor, especially for enzymes involved in sulfur metabolism and oxidation-reduction (redox) reactions. By studying its interaction with specific enzymes, scientists can gain insights into enzyme functions and regulatory mechanisms. This information is crucial for the development of new therapeutic agents targeting these enzymes.
1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid
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1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid
Required fields are marked with *
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