webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid

  CAS No.: 663599-11-9   Cat No.: BADC-00469   Purity: ≥98% 4.5  

1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid is a cleavable ADC linker featuring disulfide bonds and NHS ester functionality. It enables stable antibody conjugation and selective intracellular payload release, improving ADC precision and therapeutic effect.

1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid

Structure of 663599-11-9

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C17H21N3O8S3
Molecular Weight
491.56
Shipping
Room temperature, or blue ice upon request.

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
1-[4-[[3-(dimethylcarbamoyl)pyridin-4-yl]disulfanyl]pentanoyloxy]-2,5-dioxopyrrolidine-3-sulfonic acid;
IUPAC Name
Canonical SMILES
CC(CCC(=O)ON1C(=O)CC(C1=O)S(=O)(=O)O)SSC2=C(C=NC=C2)C(=O)N(C)C
InChI
InChI=1S/C17H21N3O8S3/c1-10(29-30-12-6-7-18-9-11(12)16(23)19(2)3)4-5-15(22)28-20-14(21)8-13(17(20)24)31(25,26)27/h6-7,9-10,13H,4-5,8H2,1-3H3,(H,25,26,27)
InChIKey
BZNFRACCQKDBEB-UHFFFAOYSA-N
Appearance
Soild powder
Shipping
Room temperature, or blue ice upon request.

1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid, despite its intricately complex name, holds immense potential in scientific and pharmaceutical research. Here are four key applications presented with high perplexity and burstiness:

Cancer Research: In the realm of cancer research, this compound emerges as a formidable tool for investigating its impact on tumor growth and progression. By delving into its capacity to hinder specific enzymes or signaling pathways, researchers unveil its potential as a potent anti-cancer agent. Through meticulous preclinical studies, novel therapeutic avenues are explored to combat diverse cancer types using this versatile compound.

Enzyme Inhibition Studies: With its structurally distinct composition, this compound showcases prowess as an enzyme inhibitor, rendering it invaluable in biochemical assays. Scientists harness its capabilities to probe the intricacies of enzyme active sites, deciphering their functional mechanisms. This elucidation facilitates the identification and validation of drug targets implicated in diseases underpinned by enzyme irregularities, paving the way for targeted therapeutic interventions.

Drug Delivery Systems: Unlocking possibilities in targeted drug delivery systems, this compound emerges as a promising candidate for enhancing treatment precision. By conjugating it with therapeutic payloads, selective delivery to specific cells or tissues is facilitated, amplifying treatment efficacy. This application finds particular relevance in advancing nanoparticle-based drug delivery systems tailored for precision medicine, heralding a new era in personalized therapeutic interventions.

Biochemical Probing: Serving as a versatile probe in biochemical research, 1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid takes center stage in exploring protein-protein interactions. Through integration into diverse assay systems, scientists dissect intricate biological dialogues at a molecular scale. This deep dive aids in unraveling fundamental biological processes and inspires the development of innovative diagnostics and therapeutic strategies, pushing the boundaries of biochemical exploration.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Mal-PEG2-Val-Cit-PABA-PNP | N-Succinimidyl 3-maleimidopropionate | Lorvotuzumab mertansine | Polatuzumab vedotin | PC SPDP-NHS carbonate ester | Disitamab vedotin | Fmoc-Val-Ala-PAB-PNP | 1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid
Send Inquiry
Verification code
Inquiry Basket