1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid combines NHS ester and disulfide chemistries to ensure stable antibody conjugation and tumor-specific payload release, optimizing ADC stability and therapeutic outcomes.
Structure of 1193111-37-3
* For research and manufacturing use only. We do not sell to patients.
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Capabilities & Facilities
1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is a specialized chemical compound with applications in biochemical research and pharmaceutical development. Here are some key applications of this compound:
Bioconjugation: 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is often used in bioconjugation reactions to link proteins, peptides, or other biomolecules. The compound's reactive groups allow for specific and stable covalent attachment of different molecules, facilitating the study of protein interactions. This enables the creation of complex biomolecular assemblies for various biomedical applications.
Drug Development: The compound is employed in the design and synthesis of novel pharmaceutical agents. Its unique chemical properties make it useful for modifying drug molecules to enhance their efficacy, stability, or selectivity. Researchers can utilize this compound to create new therapeutic candidates with improved clinical profiles.
Enzyme Inhibition Studies: 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is valuable in studying enzyme mechanisms and inhibition. By interacting with specific amino acid residues in enzyme active sites, the compound helps elucidate the roles of enzymes in metabolic pathways. This can lead to the identification of potential targets for novel inhibitors in treating various diseases.
Diagnostic Assay Development: This compound is used in the development of diagnostic assays, where it can be conjugated to antibodies or other detection molecules. The conjugates are then used in immunoassays to detect the presence of specific proteins or other biomarkers in clinical samples. Its application in diagnostics helps in early disease detection and monitoring of therapeutic responses.
Catalog | Product Name | CAS | Inquiry |
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BADC-00477 | 1-(2,5-dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid | 1193111-39-5 |
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