webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid

  CAS No.: 1193111-37-3   Cat No.: BADC-00475   Purity: ≥98% 4.5  

1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid combines NHS ester and disulfide chemistries to ensure stable antibody conjugation and tumor-specific payload release, optimizing ADC stability and therapeutic outcomes.

1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid

Structure of 1193111-37-3

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C13H13N3O9S3
Molecular Weight
451.45
Shipping
Room temperature

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
1-(2,5-dioxopyrrolidin-1-yl)oxy-4-[(5-nitropyridin-2-yl)disulfanyl]-1-oxobutane-2-sulfonic acid
IUPAC Name
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)C(CCSSC2=NC=C(C=C2)[N+](=O)[O-])S(=O)(=O)O
InChI
InChI=1S/C13H13N3O9S3/c17-11-3-4-12(18)15(11)25-13(19)9(28(22,23)24)5-6-26-27-10-2-1-8(7-14-10)16(20)21/h1-2,7,9H,3-6H2,(H,22,23,24)
InChIKey
LWDVHPVQKVSTGZ-UHFFFAOYSA-N
Appearance
Soild powder
Shipping
Room temperature

1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is a specialized chemical compound with applications in biochemical research and pharmaceutical development. Here are some key applications of this compound:

Bioconjugation: 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is often used in bioconjugation reactions to link proteins, peptides, or other biomolecules. The compound's reactive groups allow for specific and stable covalent attachment of different molecules, facilitating the study of protein interactions. This enables the creation of complex biomolecular assemblies for various biomedical applications.

Drug Development: The compound is employed in the design and synthesis of novel pharmaceutical agents. Its unique chemical properties make it useful for modifying drug molecules to enhance their efficacy, stability, or selectivity. Researchers can utilize this compound to create new therapeutic candidates with improved clinical profiles.

Enzyme Inhibition Studies: 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid is valuable in studying enzyme mechanisms and inhibition. By interacting with specific amino acid residues in enzyme active sites, the compound helps elucidate the roles of enzymes in metabolic pathways. This can lead to the identification of potential targets for novel inhibitors in treating various diseases.

Diagnostic Assay Development: This compound is used in the development of diagnostic assays, where it can be conjugated to antibodies or other detection molecules. The conjugates are then used in immunoassays to detect the presence of specific proteins or other biomarkers in clinical samples. Its application in diagnostics helps in early disease detection and monitoring of therapeutic responses.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Mal-amido-PEG8-acid | Luteolin 7-O-glucoside | 2,5-Dioxopyrrolidin-1-yl 4-((2-((2-(2-(4-(2,6-Dioxo-1,3-Dipropyl-2,3,6,9-Tetrahydro-1H-Purin-8-Yl)phenoxy)acetamido)ethyl)amino)ethyl)disulfanyl)-4-Oxobutanoate | CL2 Linker | APN-PEG4-Amine hydrochloride | APN-PEG4-DBCO | APN-PEG36-tetrazine | APN-PEG4-BCN | 14-Benzoyltalatisamine Perchlorate | Seco-DuocarmycinDME | 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid
Send Inquiry
Verification code
Inquiry Basket