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CAS No.: 1887040-81-4
Cat No.: BADC-00457
Purity: ≥98%
4.5 
4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate is a disulfide-containing crosslinker or linker building block for redox-responsive bioconjugation and ADC-related linker design. The disulfide bond provides a reduction-sensitive element, while the terminal reactive groups enable attachment to appropriately functionalized biomolecules or small-molecule partners. The molecule uses not clearly defined from product name; verify structure before assigning antibody conjugation chemistry on one side and pyridyl-disulfide / activated disulfide handle for thiol-containing payloads or thiol exchange partners on the other, with disulfide-containing spacer; exact chain length depends on structure providing the spacer/cleavable region. Conjugation orientation and reduction sensitivity should be evaluated in the context of the final construct because local substitution and neighboring groups can influence disulfide behavior.
Structure of 1887040-81-4
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4-Nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate is a versatile chemical reagent with specific applications across various scientific disciplines. Here are four key applications of this compound presented with a high degree of perplexity and burstiness:
Proteomics Research: Playing a pivotal role in proteomics, this reagent serves as a tool for labeling and modifying thiol groups in proteins. By selectively interacting with cysteine residues, researchers can delve into protein structures and interactions, shedding light on the intricate functions and dynamic behaviors of proteins within biological systems.
Drug Development: Within the realm of pharmaceuticals, 4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate emerges as a valuable agent for crafting prodrugs – a specialized form of medication that activates post-metabolic conversion. This innovative approach enhances drug solubility, stability, and bioavailability, paving the way for targeted therapeutic strategies with minimized adverse effects.
Bioconjugation: Embracing the field of bioconjugation, this compound facilitates the linking of biological molecules for a myriad of applications. By engaging with amine or sulfhydryl groups, it forms durable conjugates with peptides, proteins, or antibodies, underpinning the development of diagnostic tools, biosensors, and cutting-edge therapeutic agents essential for advancing biomedical sciences.
Chemical Biology: In the interdisciplinary realm of chemical biology, this reagent serves as a pivotal component in exploring redox biology through the modification of disulfide bonds within biomolecules. By unraveling the complexities of redox changes in cellular processes and disease pathologies, researchers gain crucial insights into new therapeutic targets and the development of redox-centric interventions aimed at addressing various health challenges.
4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate
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4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate
Required fields are marked with *
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