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Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01285 | -- | $-- | Inquiry |
Methylcyclopropene-PEG4-NHS, a versatile chemical reagent, is renowned for its ability to modify biological molecules, elevating their stability and functionality. Here are four key applications of Methylcyclopropene-PEG4-NHS:
Protein Modification: A cornerstone in protein engineering, Methylcyclopropene-PEG4-NHS is widely embraced for its prowess in attaching polyethylene glycol (PEG) moieties to proteins, a technique termed PEGylation. This transformative modification enhances protein solubility, stability, and half-life, rendering it a valuable asset in pharmaceutical realms. PEGylated proteins often exhibit mitigated immunogenicity and heightened therapeutic effectiveness, orchestrating a paradigm shift in drug development.
Drug Delivery Systems: At the forefront of innovative therapies, Methylcyclopropene-PEG4-NHS plays a pivotal role in refining drug delivery systems by optimizing the bioavailability and efficacy of therapeutic agents. Through the strategic conjugation of PEG4, drugs attain enhanced solubility and prolonged circulation within the body, culminating in amplified drug performance and targeted tissue delivery.
Biomedical Research: Serving as a catalyst in cutting-edge research endeavors, Methylcyclopropene-PEG4-NHS facilitates the exploration of intricate protein-protein interactions, offering a functional scaffold for attaching diverse biochemical probes. Researchers harness this capability to unravel the dynamics of protein networks and signaling cascades with unparalleled precision, enriching our comprehension of complex biological phenomena and disease pathogenesis.
Nanotechnology: At the nexus of scientific innovation, Methylcyclopropene-PEG4-NHS drives advancements in nanoscale carrier design for therapeutic and diagnostic applications. By leveraging PEG modification, nanoparticles acquire stealth attributes, evading immune surveillance and optimizing drug delivery mechanisms. This transformative technology amplifies the potential of nanomedicine in crafting novel treatments and cutting-edge imaging tools.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
