Name: Mal-C5-N-bis(PEG2-C2-acid)
Brand: BOC Sciences
Rating: 5 (1 reviews)

IUPAC Name

3-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethyl-[6-(2,5-dioxopyrrol-1-yl)hexanoyl]amino]ethoxy]ethoxy]propanoic acid

Canonical SMILES

C1=CC(=O)N(C1=O)CCCCCC(=O)N(CCOCCOCCC(=O)O)CCOCCOCCC(=O)O

InChI

InChI=1S/C24H38N2O11/c27-20(4-2-1-3-9-26-21(28)5-6-22(26)29)25(10-14-36-18-16-34-12-7-23(30)31)11-15-37-19-17-35-13-8-24(32)33/h5-6H,1-4,7-19H2,(H,30,31)(H,32,33)

InChIKey

OCGSASUSCDQIMT-UHFFFAOYSA-N

Mal-C5-N-bis(PEG2-C2-acid), a versatile linker molecule with diverse applications in biochemical and pharmaceutical fields, serves as a fundamental component in various processes.

Bioconjugation: Mal-C5-N-bis(PEG2-C2-acid) facilitates the covalent linkage of biomolecules, such as antibodies, enzymes, or peptides, to diverse substrates ranging from surfaces to drug carriers. This linker enhances the stability and solubility of the coupled entities, augmenting their efficacy in diagnostic or therapeutic settings. The incorporation of PEGylation components in the molecule not only enhances hydrophilicity but also mitigates immunogenicity, rendering it a preferred choice in pharmaceutical advancements.

Drug Delivery Systems: Mal-C5-N-bis(PEG2-C2-acid) assumes a pivotal role in the development of sophisticated drug delivery platforms. By enabling the attachment of therapeutic agents to carrier molecules like nanoparticles or liposomes, it facilitates controlled drug release and targeted delivery to specific cellular locales. This precise approach proves beneficial in enhancing drug efficacy while minimizing adverse effects associated with chemotherapeutic medications.

Surface Modification: Mal-C5-N-bis(PEG2-C2-acid) enhances the functionality of biomedical devices and implants by conjugating bioactive molecules onto their surfaces. This strategic modification not only augments biocompatibility but also alleviates biofouling, facilitating desired interactions with biological systems. Such advancements are critical in diverse applications, including sensor technology, tissue engineering, and orthopedic implant developments.

Biophysical Studies: Embraced in biophysical investigations, the linker molecule aids in the exploration of intricate protein-protein interactions and conformational alterations. By cross-linking proteins or introducing detectable labels, Mal-C5-N-bis(PEG2-C2-acid) empowers researchers to delve into dynamic biological phenomena at a molecular scale.