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m-C-tri(CH2-PEG1-NHS ester) signifies a multifaceted and utilitarian agent extensively employed within the realm of biomedicine. Its profound versatility lies in its adeptness as a reactive entity, facilitating the intricate conjugation of pharmaceuticals or biomolecular entities to meticulously designated targets.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00374 | 100 mg | $439 | Inquiry |
m-C-tri(CH2-PEG1-NHS ester) is a versatile chemical reagent used primarily for bioconjugation and surface modification applications. Here are some key applications of m-C-tri(CH2-PEG1-NHS ester):
Bioconjugation: m-C-tri(CH2-PEG1-NHS ester) is widely used for the conjugation of biomolecules such as proteins, antibodies, and peptides. The NHS ester group readily reacts with primary amine groups on these biomolecules, forming stable amide bonds. This facilitates the creation of functionalized biomolecule conjugates that can be used in diagnostic assays and therapeutic applications.
Surface Modification: This compound is used in modifying surfaces to improve biocompatibility and prevent nonspecific binding in biomedical devices. By attaching m-C-tri(CH2-PEG1-NHS ester) to surfaces, a hydrophilic PEG layer is formed, which reduces protein adsorption and cell adhesion. This application is vital in the fabrication of biosensors and implantable devices where surface performance is crucial.
Drug Delivery Systems: m-C-tri(CH2-PEG1-NHS ester) is employed in the development of drug delivery systems that require polyethylene glycol (PEG) modification. By conjugating PEG to drug molecules or carriers, the solubility and stability of drugs can be enhanced while also prolonging their circulation time in the bloodstream. This PEGylation process helps in achieving better therapeutic outcomes and reducing immunogenicity.
Nanoparticle Functionalization: In nanotechnology, m-C-tri(CH2-PEG1-NHS ester) is used to functionalize nanoparticles, improving their dispersion and stability in biological systems. The compound enables the attachment of targeting ligands to nanoparticle surfaces, facilitating targeted delivery of therapeutics to specific tissues or cells. This application is important for advancing precision medicine and the efficacy of nanoparticle-based therapies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
