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Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00677 | -- | $-- | Inquiry |
Fmoc-PEA, a modified amino acid with diverse applications in peptide synthesis and biochemistry, boasts versatility and utility in various fields. Here are four key applications of Fmoc-PEA:
Peptide Synthesis: Serving as a fundamental building block in the intricate realm of peptide and protein synthesis, Fmoc-PEA plays a crucial role. Its Fmoc protective group facilitates the sequential addition of amino acids in solid-phase peptide synthesis (SPPS), ensuring the creation of highly pure and efficient custom peptides tailored for both research and therapeutic endeavors.
Bioconjugation: Delving into the realm of bioconjugation, Fmoc-PEA emerges as a key player in the fusion of peptides with other biomolecules, yielding bioconjugates of immense significance. This strategic linkage gives rise to a new class of molecules vital for the development of peptide-based drugs, diagnostic tools, and imaging agents. The conjugation process not only enhances the functionality and specificity of peptides but also amplifies their efficacy in diverse applications.
Structure-Activity Relationship (SAR) Studies: In the domain of SAR studies, Fmoc-PEA stands as an indispensable tool for unraveling the intricate connections between peptide structure and biological activities. By integrating Fmoc-PEA into diverse peptide sequences, researchers can discern variations in activity, binding affinity, and stability.
Protein Engineering: As a pivotal component in protein engineering, Fmoc-PEA drives innovation in the creation of novel proteins with enhanced functionalities and properties. Through its targeted incorporation into protein sequences, researchers can finely tune protein characteristics such as stability, activity, and binding interactions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
