Apaziquone - CAS 141304-51-0 Catalog number: BADC-00593
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Apaziquone is an indolequinone bioreductive prodrug and analog of mitomycin C with potential antineoplastic and radiosensitization activities. Apaziquone is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.