ADCs Cytotoxin with Linkers
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ADCs Cytotoxin with Linkers

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Catalog Product Name CAS Number
BADC-00870 SPB 858128-57-1
SPB is a drug-linker conjugate for ADC with potent anti-inflammatory activity by using Xanthotoxol, linked via the ADC linker. Inquiry
BADC-00018 sulfo-SPDB-DM4 1626359-59-8
DM4 with a reactive linker sulfo-SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Inquiry
BADC-00030 BA-3011
BA-3011 is a novel conditionally active biologic AXL-targeted antibody-drug conjugate used to treat solid tumor. The CAB technology is aimed to improve the selectivity of BA-3011 for binding to AXL receptor on cancer cells. Inquiry
BADC-00852 Mc-Dexamethasone 1618096-56-2
Mc-Dexamethasone is a drug-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. Inquiry
BADC-00858 MC-Val-Cit-PAB-rifabutin 2055900-34-8
MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate for ADC with potent antitumor activity by using rifabutin (an DNA-dependent RNA polymerase inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Inquiry
BADC-00859 DGN549-C 2058075-34-4
DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01344 IgG1-VcMMAE
IgG1-VcMMAE is an anti-mesothelin antibody-drug conjugate that eradicates mesothelin-positive human gastric and pancreatic tumors in xenograft models. Inquiry
BADC-01349 Azido-PEG4-Glu-Val-Cit-PAB-MMAE
Azido-PEG4-Glu-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Inquiry
BADC-01426 VA-PAB-DMEA-PNU159682 2414872-62-9
VA-PAB-DMEA-PNU159682 is a sortase-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01535 MC-VC-PAB-Tubulysin M 1639939-56-2
MC-VC-PAB-Tubulysin M is a potent antibody-drug conjugate used in the treatment of various cancers, including breast, lung, and ovarian cancers. It combines the targeted delivery of an antibody with the cytotoxic effects of Tubulysin M, inhibiting microtubule formation and inducing cell death. Inquiry
BADC-00029 MC-Val-Cit-PAB-MMAE 646502-53-6
MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Inquiry
BADC-00028 DOXO-EMCH 151038-96-9
DOXO-EMCH is an albumin-binding prodrug of doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Inquiry
BADC-00027 INNO-206 1361644-26-9
INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Inquiry
BADC-00026 Mc-MMAD 1401963-15-2
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. Inquiry
BADC-00024 Vc-MMAD 1401963-17-4
Vc-MMAD consists the ADCs linker(Val-Cit) and potent tubulin inhibitor (MMAD), Vc-MMAD is an antibody drug conjugate. Inquiry
BADC-00025 Mc-MMAE 863971-24-8
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Inquiry
BADC-00020 DM1-SMe 138148-68-2
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). . Inquiry
BADC-00019 Fmoc-VC-PAB-MMAE 1350456-56-2
Fmoc-Val-Cit-PAB-MMAE is an antibody drug conjugate contained Fmoc-Val-Cit-PAB and MMAE and probably have antineoplastic activity. Inquiry
BADC-00849 Acetylene-linker-Val-Cit-PABC-MMAE 1411977-95-1
Acetylene-linker-Val-Cit-PABC-MMAE consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE), Acetylene-linker-Val-Cit-PABC-MMAE is an antibody drug conjugate. Inquiry
BADC-01448 mDPR-Val-Cit-PAB-MMAE 1491152-26-1
mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate. Inquiry
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