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ADCs Cytotoxin with Linkers
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ADCs Cytotoxin with Linkers

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Catalog Product Name CAS Number
BADC-00015 MC-Val-Ala-PBD 1342820-51-2
MC-Val-Ala-PBD is a protective group conjugated PBD, PBD bind in the minor groove of DNA. Inquiry
BADC-00017 DM4-SMCC 1228105-52-9
DM4 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Inquiry
BADC-00018 sulfo-SPDB-DM4 1626359-59-8
DM4 with a reactive linker sulfo-SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Inquiry
BADC-00019 Fmoc-VC-PAB-MMAE 1350456-56-2
Fmoc-Val-Cit-PAB-MMAE is an antibody drug conjugate contained Fmoc-Val-Cit-PAB and MMAE and probably have antineoplastic activity. Inquiry
BADC-00024 Vc-MMAD 1401963-17-4
Vc-MMAD consists the ADCs linker(Val-Cit) and potent tubulin inhibitor (MMAD), Vc-MMAD is an antibody drug conjugate. Inquiry
BADC-00026 Mc-MMAD 1401963-15-2
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. Inquiry
BADC-00027 INNO-206 1361644-26-9
INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Inquiry
BADC-00028 DOXO-EMCH 151038-96-9
DOXO-EMCH is an albumin-binding prodrug of doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Inquiry
BADC-00030 BA-3011
BA-3011 is a novel conditionally active biologic AXL-targeted antibody-drug conjugate used to treat solid tumor. The CAB technology is aimed to improve the selectivity of BA-3011 for binding to AXL receptor on cancer cells. Inquiry
BADC-00574 Lys-SMCC-DM1 1281816-04-3
Lys-SMCC-DM1 is the active metabolite of DM1. DM1 is a tubulin inhibitor. Inquiry
BADC-00585 Vc-seco-DUBA 1345681-58-4
Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco. Inquiry
BADC-00592 MC-Alkyl-Hydrazine Modified MMAF 1404071-64-2
MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine. Inquiry
BADC-00594 PEG4-aminooxy-MMAF 1415246-35-3
PEG4-aminooxy-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4. Inquiry
BADC-00596 AcLys-PABC-VC-Aur0101 1438851-17-2
AcLys-PABC-VC-Aur0101 is a cleavable anti-CXCR4 drug-linker conjugates for ADC. It has potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the cleavable linker AcLys-PABC-VC. Inquiry
BADC-00600 Sulfo-PDBA-DM4 1461704-01-7
Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker. Inquiry
BADC-00601 Mal-VC-PAB-DM1 1464051-44-2
Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB. Inquiry
BADC-00604 Mal-C6-α-Amanitin 1578249-76-9
Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6. Inquiry
BADC-00608 MC-GGFG-DX8951 1600418-29-8
MC-GGFG-DX8951 is a DX8951 derivative with MC-GGFG linker, in which DX8951 was covalently connected via a peptidyl spacer (Gly-Gly-Phe-Gly), which is assumed to be stable in circulation, and were cleaved by lysosomal enzymes following ADC internalization into tumor tissue. MC-GGFG-DX8951 is very useful to prepare DX8951 antibody conjugate (ADC). Inquiry
BADC-00611 MC-Val-Cit-PAB-clindamycin 1639793-13-7
MC-Val-Cit-PAB-clindamycin is a drug-linker conjugate for ADC with potent antitumor activity by using clindamycin (a protein synthesis inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Inquiry
BADC-00612 MC-Val-Cit-PAB-Retapamulin 1639793-15-9
MC-Val-Cit-PAB-retapamulin has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-retapamulin is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders. Inquiry
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