Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00613 | AmPEG6C2-Aur0131 | 1650569-94-0 |
| AmPEG6C2-Aur0131 is a drug-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2. | Inquiry | |
| BADC-00619 | AZ1508 | 1817736-04-1 |
| AZ1508 is a drug-linker conjugates for ADC for the treatment of breast and stomach cancer, and the drug is a tubulin inhibitor. | Inquiry | |
| BADC-00623 | MC-Sq-Cit-PAB-Gefitinib | 1941168-63-3 |
| MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB. | Inquiry | |
| BADC-00624 | MC-Sq-Cit-PAB-Dolastatin10 | 1941168-65-5 |
| MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB. | Inquiry | |
| BADC-00625 | Nitro-PDS-Tubulysin M | 1941168-69-9 |
| Nitro-PDS-Tubulysin M is a drug-linker conjugate for ADC with potent antitumor activity by using Tubulysin M (a tubulin polymerization inhibitor), linked via the ADC linker Nitro-PDS. | Inquiry | |
| BADC-00629 | MC-Val-Cit-PAB-Auristatin E | 2055896-77-8 |
| MC-Val-Cit-PAB-Auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00630 | MC-Val-Cit-PAB-carfilzomib | 2055896-83-6 |
| MC-Val-Cit-PAB-carfilzomib is a drug-linker conjugate for ADC with potent antitumor activity by using carfilzomib (an irreversible proteasome inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00631 | MC-Val-Cit-PAB-tubulysin5a | 2055896-86-9 |
| MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00632 | MC-Val-Cit-PAB-Indibulin | 2055896-95-0 |
| MC-Val-Cit-PAB-Indibulin is a drug-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00633 | MC-Val-Cit-PAB-duocarmycin | 2055896-98-3 |
| MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00660 | VCP-Eribulin | 2130869-17-7 |
| VCP-Eribulin consists the ADCs linker (VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. VCP-Eribulin is an Eribulin-based drug for antibody conjugates. | Inquiry | |
| BADC-00666 | MAC glucuronide phenol-linked SN-38 | 2246380-69-6 |
| MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. | Inquiry | |
| BADC-00667 | MAC glucuronide α-hydroxy lactone-linked SN-38 | 2246380-70-9 |
| MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively. | Inquiry | |
| BADC-00668 | SC-VC-PAB-DM1 | 2259318-47-1 |
| SC-VC-PAB-DM1 is a drug-linker conjugate for ADC with with potent antitumor activity by using DM1 (Mertansine, a tubulin inhibitor) , linked via the ADC linker SC-VC-PAB. | Inquiry | |
| BADC-00669 | Mal-VC-PAB-ABAEP-Azonafide | 2259318-48-2 |
| Mal-VC-PAB-ABAEP-Azonafide is a drug-linker conjugate for ADC with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB. | Inquiry | |
| BADC-00670 | Mal-PEG4-VA-PBD | 2259318-50-6 |
| Mal-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA. | Inquiry | |
| BADC-00671 | Mal-C2-Gly3-EDA-PNU-159682 | 2259318-53-9 |
| Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-00685 | MCC-Modified Daunorubicinol | 721945-30-8 |
| Daunorubicinol is a drug-linker conjugate for ADC with potent antitumor activity by using Aur0101 (DNA Topoisomerase II inhibitor), linked via the ADC linker. | Inquiry | |
| BADC-00694 | MMAF-OMe | 863971-12-4 |
| MMAF-Ome is a methoxyl analogue of MMAF, used in antibody-drug conjugates (ADCs) as the antimitotic agent part. The methoxyl works as the reaction group. MMAF is a potent auristatin-derived antineoplastic agent, working by inhibition of tubulin polymerization. It exhibited cytotoxicity in Karpas 299, H3396, 786-O and Caki-1 cells with IC50 values of 119nM, 105nM, 257nM and 200nM after 96-hour treatment. | Inquiry | |
| BADC-00696 | Val-Cit-PAB-MMAF | 863971-56-6 |
| Val-Cit-PAB-MMAF is an antibody drug conjugate cytotoxin. | Inquiry |
