Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00623 | MC-Sq-Cit-PAB-Gefitinib | 1941168-63-3 |
| MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB. | Inquiry | |
| BADC-00624 | MC-Sq-Cit-PAB-Dolastatin10 | 1941168-65-5 |
| MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB. | Inquiry | |
| BADC-00625 | Nitro-PDS-Tubulysin M | 1941168-69-9 |
| Nitro-PDS-Tubulysin M is a drug-linker conjugate for ADC with potent antitumor activity by using Tubulysin M (a tubulin polymerization inhibitor), linked via the ADC linker Nitro-PDS. | Inquiry | |
| BADC-00629 | MC-Val-Cit-PAB-Auristatin E | 2055896-77-8 |
| MC-Val-Cit-PAB-Auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00630 | MC-Val-Cit-PAB-carfilzomib | 2055896-83-6 |
| MC-Val-Cit-PAB-carfilzomib is a drug-linker conjugate for ADC with potent antitumor activity by using carfilzomib (an irreversible proteasome inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00631 | MC-Val-Cit-PAB-tubulysin5a | 2055896-86-9 |
| MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00632 | MC-Val-Cit-PAB-Indibulin | 2055896-95-0 |
| MC-Val-Cit-PAB-Indibulin is a drug-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00633 | MC-Val-Cit-PAB-duocarmycin | 2055896-98-3 |
| MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00660 | VCP-Eribulin | 2130869-17-7 |
| VCP-Eribulin consists the ADCs linker (VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. VCP-Eribulin is an Eribulin-based drug for antibody conjugates. | Inquiry | |
| BADC-00666 | MAC glucuronide phenol-linked SN-38 | 2246380-69-6 |
| MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. | Inquiry | |
| BADC-00667 | MAC glucuronide α-hydroxy lactone-linked SN-38 | 2246380-70-9 |
| MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively. | Inquiry | |
| BADC-00668 | SC-VC-PAB-DM1 | 2259318-47-1 |
| SC-VC-PAB-DM1 is a drug-linker conjugate for ADC with with potent antitumor activity by using DM1 (Mertansine, a tubulin inhibitor) , linked via the ADC linker SC-VC-PAB. | Inquiry | |
| BADC-00669 | Mal-VC-PAB-ABAEP-Azonafide | 2259318-48-2 |
| Mal-VC-PAB-ABAEP-Azonafide is a drug-linker conjugate for ADC with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB. | Inquiry | |
| BADC-00670 | Mal-PEG4-VA-PBD | 2259318-50-6 |
| Mal-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA. | Inquiry | |
| BADC-00671 | Mal-C2-Gly3-EDA-PNU-159682 | 2259318-53-9 |
| Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-00685 | MCC-Modified Daunorubicinol | 721945-30-8 |
| Daunorubicinol is a drug-linker conjugate for ADC with potent antitumor activity by using Aur0101 (DNA Topoisomerase II inhibitor), linked via the ADC linker. | Inquiry | |
| BADC-00694 | MMAF-OMe | 863971-12-4 |
| MMAF-Ome is a methoxyl analogue of MMAF, used in antibody-drug conjugates (ADCs) as the antimitotic agent part. The methoxyl works as the reaction group. MMAF is a potent auristatin-derived antineoplastic agent, working by inhibition of tubulin polymerization. It exhibited cytotoxicity in Karpas 299, H3396, 786-O and Caki-1 cells with IC50 values of 119nM, 105nM, 257nM and 200nM after 96-hour treatment. | Inquiry | |
| BADC-00696 | Val-Cit-PAB-MMAF | 863971-56-6 |
| Val-Cit-PAB-MMAF is an antibody drug conjugate cytotoxin. | Inquiry | |
| BADC-00704 | DBA-DM4 | 905449-84-5 |
| DBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody drug conjugate (ADC). | Inquiry | |
| BADC-00724 | ALPHA-AMANITIN | 23109-05-9 |
| α-Amanitin is produced by the strain of Amanita phalloides. It is highly toxic to humans and can cause salivation, vomiting, bleeding, diarrhea, cyanosis, muscle convulsions, spasms, and death. It is the principal toxin of several deadly poisonous mushrooms and exerts its toxic effects by inhibiting RNA polymerase II. | Inquiry |
