Inquiry Basket
Catalog | Product Name | CAS Number |
---|---|---|
BADC-00633 | MC-Val-Cit-PAB-duocarmycin | 2055896-98-3 |
MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
BADC-00660 | VCP-Eribulin | 2130869-17-7 |
VCP-Eribulin consists the ADCs linker (VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. VCP-Eribulin is an Eribulin-based drug for antibody conjugates. | Inquiry | |
BADC-00666 | MAC glucuronide phenol-linked SN-38 | 2246380-69-6 |
MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. | Inquiry | |
BADC-00667 | MAC glucuronide α-hydroxy lactone-linked SN-38 | 2246380-70-9 |
MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively. | Inquiry | |
BADC-00668 | SC-VC-PAB-DM1 | 2259318-47-1 |
SC-VC-PAB-DM1 is a drug-linker conjugate for ADC with with potent antitumor activity by using DM1 (Mertansine, a tubulin inhibitor) , linked via the ADC linker SC-VC-PAB. | Inquiry | |
BADC-00669 | Mal-VC-PAB-ABAEP-Azonafide | 2259318-48-2 |
Mal-VC-PAB-ABAEP-Azonafide is a drug-linker conjugate for ADC with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB. | Inquiry | |
BADC-00670 | Mal-PEG4-VA-PBD | 2259318-50-6 |
Mal-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA. | Inquiry | |
BADC-00671 | Mal-C2-Gly3-EDA-PNU-159682 | 2259318-53-9 |
Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682. | Inquiry | |
BADC-00685 | MCC-Modified Daunorubicinol | 721945-30-8 |
Daunorubicinol is a drug-linker conjugate for ADC with potent antitumor activity by using Aur0101 (DNA Topoisomerase II inhibitor), linked via the ADC linker. | Inquiry | |
BADC-00694 | MMAF-OMe | 863971-12-4 |
MMAF-Ome is a methoxyl analogue of MMAF, used in antibody-drug conjugates (ADCs) as the antimitotic agent part. The methoxyl works as the reaction group. MMAF is a potent auristatin-derived antineoplastic agent, working by inhibition of tubulin polymerization. It exhibited cytotoxicity in Karpas 299, H3396, 786-O and Caki-1 cells with IC50 values of 119nM, 105nM, 257nM and 200nM after 96-hour treatment. | Inquiry | |
BADC-00696 | Val-Cit-PAB-MMAF | 863971-56-6 |
Val-Cit-PAB-MMAF is an antibody drug conjugate cytotoxin. | Inquiry | |
BADC-00704 | DBA-DM4 | 905449-84-5 |
DBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody drug conjugate (ADC). | Inquiry | |
BADC-00725 | OSu-Glu-vc-PAB-MMAE | |
OSu-Glu-vc-PAB-MMAE is a drug-linker conjugate for ADC by using monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via OSu-Glu-vc-PAB. | Inquiry | |
BADC-00726 | OSu-PEG4-vc-PAB-DMEA-Duocarmycin SA | |
OSu-PEG4-vc-PAB-DMEA-Duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via OSu-PEG4-vc-PAB-DMEA. | Inquiry | |
BADC-00727 | Mylotarg-linker | |
Mylotarg-linker is a drug-linker conjugate for ADC by using N-Acetyl-Calicheamicin and Osu-AcBut-acetyl hydrozide derivative. | Inquiry | |
BADC-00728 | OSu-Glu-vc-PAB-MMAD | |
OSu-Glu-vc-PAB-MMAD is a drug-linker conjugate for ADC by using Monomethyl Dolastatin 10 (MMAD, a potent tubulin inhibitor), linked via OSu-Glu-vc-PAB. | Inquiry | |
BADC-00729 | OSu-PEG4-vc-PAB-DMEA-Duocarmycin TM | |
OSu-PEG4-vc-PAB-DMEA-Duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via OSu-PEG4-vc-PAB-DMEA. | Inquiry | |
BADC-00730 | OSu-PEG4-vc-PAB-DMEA-Duocarmycin DM | |
OSu-PEG4-vc-PAB-DMEA-Duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via OSu-PEG4-vc-PAB-DMEA. | Inquiry | |
BADC-00731 | MC-MMD-10 | |
MC-MMD-10 is a drug-linker conjugate for ADC by using MMD-10 and the linker MC. | Inquiry | |
BADC-00732 | MA-PEG4-vc-PAB-DMEA-duocarmycin SA | |
MA-PEG4-vc-PAB-DMEA-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. | Inquiry |