ADCs Cytotoxin with Linkers
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ADCs Cytotoxin with Linkers

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Catalog Product Name CAS Number
BADC-00854 Mc-VC-PAB-SN38 1801838-28-7
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00855 SuO-Glu-Val-Cit-PAB-MMAE 1895916-24-1
SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00856 MMAE-SMCC 2021179-11-1
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate. Inquiry
BADC-00857 MC-Val-Cit-PAB-vinblastine 2055896-92-7
MC-Val-Cit-PAB-vinblastine is a drug-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Inquiry
BADC-00860 Mal-PEG2-VCP-Eribulin 2130869-18-8
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates. Inquiry
BADC-00861 NAMPT inhibitor-linker 2 2241014-82-2
NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively. Inquiry
BADC-00862 NAMPT inhibitor-linker 1 2241019-57-6
NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC50s of <3 pM and 9 pM, respectively. Inquiry
BADC-00863 DBCO-PEG4-Val-Cit-PAB-MMAF 2244602-23-9
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00864 SC-VC-PAB-MMAE 2259318-46-0
SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB. Inquiry
BADC-00865 Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA 2259318-49-3
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco. Inquiry
BADC-00866 Mal-Phe-C4-VC-PAB-MMAE 2259318-51-7
Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. Inquiry
BADC-00867 Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 2259318-54-0
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. Inquiry
BADC-00868 DBCO-(PEG2-VC-PAB-MMAE)2 2259318-55-1
DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. Inquiry
BADC-00869 AcLysValCit-PABC-DMAE-SW-163D 2411007-69-5
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker. Inquiry
BADC-00871 Fmoc-Val-Cit-PAB-Duocarmycin TM
Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB. Inquiry
BADC-00872 Gemcitabine-O-Si(di-iso)-O-Mc
Gemcitabine-O-Si(di-iso)-O-Mc is a drug-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker. Inquiry
BADC-00724 ALPHA-AMANITIN 23109-05-9
α-Amanitin is produced by the strain of Amanita phalloides. It is highly toxic to humans and can cause salivation, vomiting, bleeding, diarrhea, cyanosis, muscle convulsions, spasms, and death. It is the principal toxin of several deadly poisonous mushrooms and exerts its toxic effects by inhibiting RNA polymerase II. Inquiry
BADC-01454 2',3'-cGAMP-C2-PPA 2586047-11-0
2',3'-cGAMP-C2-PPA (45), a cyclic dinucleotide, is a STING agonist (US20210015941A1). 2',3'-cGAMP-C2-PPA is a part of antibody-linker conjugate for ADC (drug-linker conjugate for ADC), which can be used to synthesize antibody conjugates for targeted cancer research. Inquiry
BADC-01340 Gly3-VC-PAB-MMAE 2684216-48-4
Gly3-VC-PAB-MMAE is a drug-linker conjugate for ADC consisting of a cleavable ADC linker (Gly3-VC-PAB) and a potent tubulin inhibitor (MMAE). Inquiry
BADC-01350 Azido-PEG4-Val-Cit-MMAE
Azido-PEG4-Val-Cit-MMAE is a drug-linker conjugate for ADC. Inquiry
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