Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00860 | Mal-PEG2-VCP-Eribulin | 2130869-18-8 |
| Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates. | Inquiry | |
| BADC-00861 | NAMPT inhibitor-linker 2 | 2241014-82-2 |
| NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively. | Inquiry | |
| BADC-00862 | NAMPT inhibitor-linker 1 | 2241019-57-6 |
| NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC50s of <3 pM and 9 pM, respectively. | Inquiry | |
| BADC-00863 | DBCO-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 |
| DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
| BADC-00864 | SC-VC-PAB-MMAE | 2259318-46-0 |
| SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB. | Inquiry | |
| BADC-00865 | Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA | 2259318-49-3 |
| Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco. | Inquiry | |
| BADC-00866 | Mal-Phe-C4-VC-PAB-MMAE | 2259318-51-7 |
| Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. | Inquiry | |
| BADC-00867 | Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 | 2259318-54-0 |
| Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-00868 | DBCO-(PEG2-VC-PAB-MMAE)2 | 2259318-55-1 |
| DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. | Inquiry | |
| BADC-00869 | AcLysValCit-PABC-DMAE-SW-163D | 2411007-69-5 |
| AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker. | Inquiry | |
| BADC-00870 | SPB | 858128-57-1 |
| SPB is a drug-linker conjugate for ADC with potent anti-inflammatory activity by using Xanthotoxol, linked via the ADC linker. | Inquiry | |
| BADC-00871 | Fmoc-Val-Cit-PAB-Duocarmycin TM | |
| Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB. | Inquiry | |
| BADC-00872 | Gemcitabine-O-Si(di-iso)-O-Mc | |
| Gemcitabine-O-Si(di-iso)-O-Mc is a drug-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker. | Inquiry | |
| BADC-01344 | IgG1-VcMMAE | |
| IgG1-VcMMAE is an anti-mesothelin antibody-drug conjugate that eradicates mesothelin-positive human gastric and pancreatic tumors in xenograft models. | Inquiry | |
| BADC-01349 | Azido-PEG4-Glu-Val-Cit-PAB-MMAE | |
| Azido-PEG4-Glu-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. | Inquiry | |
| BADC-01350 | Azido-PEG4-Val-Cit-MMAE | |
| Azido-PEG4-Val-Cit-MMAE is a drug-linker conjugate for ADC. | Inquiry | |
| BADC-01406 | Ozogamicin | 400046-53-9 |
| Ozogamicin is a drug-linker conjugates for ADC. Ozogamicin can be used in the synthesis of gemtuzumab ozogamicin and inotuzumab ozogamicin. | Inquiry | |
| BADC-01407 | SPDB-DM1 | |
| SPDB-DM1 is a mertansine-linked drug that is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-01408 | DBM(C6)-VC-PAB-MMAE | 1644228-55-6 |
| DBM(C6)-VC-PAB-MMAE is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
| BADC-01409 | Mal-PEG4-VC-PAB-EDA-PNU159682 | 2571582-15-3 |
| Mal-PEG4-VC-PAB-EDA-PNU159682 is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry |
