Inquiry Basket
Catalog | Product Name | CAS Number |
---|---|---|
BADC-00854 | Mc-VC-PAB-SN38 | 1801838-28-7 |
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-00855 | SuO-Glu-Val-Cit-PAB-MMAE | 1895916-24-1 |
SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-00856 | MMAE-SMCC | 2021179-11-1 |
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate. | Inquiry | |
BADC-00857 | MC-Val-Cit-PAB-vinblastine | 2055896-92-7 |
MC-Val-Cit-PAB-vinblastine is a drug-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
BADC-00860 | Mal-PEG2-VCP-Eribulin | 2130869-18-8 |
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates. | Inquiry | |
BADC-00861 | NAMPT inhibitor-linker 2 | 2241014-82-2 |
NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively. | Inquiry | |
BADC-00862 | NAMPT inhibitor-linker 1 | 2241019-57-6 |
NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC50s of <3 pM and 9 pM, respectively. | Inquiry | |
BADC-00863 | DBCO-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 |
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-00864 | SC-VC-PAB-MMAE | 2259318-46-0 |
SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB. | Inquiry | |
BADC-00865 | Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA | 2259318-49-3 |
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco. | Inquiry | |
BADC-00866 | Mal-Phe-C4-VC-PAB-MMAE | 2259318-51-7 |
Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. | Inquiry | |
BADC-00867 | Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 | 2259318-54-0 |
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. | Inquiry | |
BADC-00868 | DBCO-(PEG2-VC-PAB-MMAE)2 | 2259318-55-1 |
DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. | Inquiry | |
BADC-00869 | AcLysValCit-PABC-DMAE-SW-163D | 2411007-69-5 |
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker. | Inquiry | |
BADC-00871 | Fmoc-Val-Cit-PAB-Duocarmycin TM | |
Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB. | Inquiry | |
BADC-00872 | Gemcitabine-O-Si(di-iso)-O-Mc | |
Gemcitabine-O-Si(di-iso)-O-Mc is a drug-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker. | Inquiry | |
BADC-00724 | ALPHA-AMANITIN | 23109-05-9 |
α-Amanitin is produced by the strain of Amanita phalloides. It is highly toxic to humans and can cause salivation, vomiting, bleeding, diarrhea, cyanosis, muscle convulsions, spasms, and death. It is the principal toxin of several deadly poisonous mushrooms and exerts its toxic effects by inhibiting RNA polymerase II. | Inquiry | |
BADC-01454 | 2',3'-cGAMP-C2-PPA | 2586047-11-0 |
2',3'-cGAMP-C2-PPA (45), a cyclic dinucleotide, is a STING agonist (US20210015941A1). 2',3'-cGAMP-C2-PPA is a part of antibody-linker conjugate for ADC (drug-linker conjugate for ADC), which can be used to synthesize antibody conjugates for targeted cancer research. | Inquiry | |
BADC-01340 | Gly3-VC-PAB-MMAE | 2684216-48-4 |
Gly3-VC-PAB-MMAE is a drug-linker conjugate for ADC consisting of a cleavable ADC linker (Gly3-VC-PAB) and a potent tubulin inhibitor (MMAE). | Inquiry | |
BADC-01350 | Azido-PEG4-Val-Cit-MMAE | |
Azido-PEG4-Val-Cit-MMAE is a drug-linker conjugate for ADC. | Inquiry |