DBA-DM4 - CAS 905449-84-5

DBA-DM4 - CAS 905449-84-5 Catalog number: BADC-00704

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

DBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody drug conjugate (ADC).

General Information

Category
ADCs Cytotoxin with Linkers
Product Name
DBA-DM4
CAS
905449-84-5
Catalog Number
BADC-00704
Molecular Formula
C42H60ClN3O12S2
Molecular Weight
898.52

Chemical Structure

  • DBA-DM4
Synonyms
4-[[5-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-2-methyl-5-oxopentan-2-yl]disulfanyl]butanoic acid
Shipping
Room temperature, or blue ice upon request.
Canonical SMILES
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)O)C)C)OC)(NC(=O)O2)O
InChI Key
ORSKCTIDJPPMJJ-CYZHRDLYSA-N
InChI
InChI=1S/C42H60ClN3O12S2/c1-24-13-11-14-31(55-10)42(53)23-30(56-39(52)44-42)25(2)37-41(6,58-37)32(22-34(48)46(8)28-20-27(19-24)21-29(54-9)36(28)43)57-38(51)26(3)45(7)33(47)16-17-40(4,5)60-59-18-12-15-35(49)50/h11,13-14,20-21,25-26,30-32,37,53H,12,15-19,22-23H2,1-10H3,(H,44,52)(H,49,50)/b14-11+,24-13+/t25-,26+,30+,31-,32+,37+,41+,42+/m1/s1

Related Products

Get in Touch

Verification code
Historical Records: OSu-PEG4-vc-PAB-DMEA-Duocarmycin DM | DBCO-PEG4-DMEA-PNU159682 | Calicheamicin | MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA | Mal-VC-PAB-DM1 | Fmoc-VC-PAB-MMAE | DBCO-(PEG)3-VC-PAB-MMAE | Exatecan Mesylate | endo-BCN-PEG4-NHS ester | DBCO-PEG4-vc-PAB-MMAE | DBA-DM4
Inquiry Basket