Inquiry Basket
N-(2-Oxotetrahydrofuran-3-yl)butyramide is a linker widely used in antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01539 | -- | $-- | Inquiry |
N-(2-Oxotetrahydrofuran-3-yl)butyramide is a unique chemical compound with a tetrahydrofuran (THF) ring system attached to a butyramide group. This structure imparts interesting bioactive properties to the compound, making it an attractive candidate in medicinal chemistry and drug development. The THF ring system is known for its ability to interact with various enzymes and receptors, while the butyramide moiety can potentially engage in important biological interactions. As a result, this compound has promising applications in fields such as enzyme inhibition, cancer therapy, and drug discovery.
One of the most significant applications of N-(2-Oxotetrahydrofuran-3-yl)butyramide is in the development of enzyme inhibitors. The tetrahydrofuran ring is a versatile pharmacophore that can mimic natural substrates or transition states of enzymes, making it an effective scaffold for the design of enzyme inhibitors. This compound could be used to inhibit key enzymes involved in cellular processes, such as kinases, proteases, or metabolic enzymes. By selectively targeting these enzymes, N-(2-Oxotetrahydrofuran-3-yl)butyramide has the potential to modulate various biological pathways, including those involved in cancer, inflammation, and metabolic disorders. Enzyme inhibition could lead to therapeutic benefits in diseases characterized by overactive or dysregulated enzyme activity.
In cancer therapy, N-(2-Oxotetrahydrofuran-3-yl)butyramide may be valuable for targeting cancer cell growth and proliferation. The compound’s structure suggests that it may interact with molecular targets that regulate cell cycle progression or apoptosis. The ability to inhibit enzymes involved in these processes could disrupt tumor cell growth and enhance the effectiveness of existing cancer treatments. Additionally, the compound's specificity could reduce the side effects typically associated with conventional chemotherapy. By offering a targeted approach, N-(2-Oxotetrahydrofuran-3-yl)butyramide could potentially improve the precision and safety of cancer therapies, particularly in treating solid tumors that are difficult to target with current treatments.
Another promising application of this compound is in drug delivery systems. The tetrahydrofuran ring is often used in drug design to enhance solubility and bioavailability, making N-(2-Oxotetrahydrofuran-3-yl)butyramide a suitable candidate for incorporation into drug delivery formulations. Its ability to interact with biological membranes could help improve the compound's ability to cross cell barriers, ensuring better delivery of therapeutic agents. When conjugated with other bioactive molecules, N-(2-Oxotetrahydrofuran-3-yl)butyramide could serve as a linker in prodrug systems, allowing for the controlled release of active pharmaceutical ingredients at the desired site of action, reducing toxicity and enhancing treatment efficacy.
Finally, N-(2-Oxotetrahydrofuran-3-yl)butyramide can play a key role in high-throughput screening and drug discovery. Its unique structure and potential for enzyme modulation make it a valuable tool for screening libraries of small molecules for therapeutic activity. Researchers can use this compound as a lead molecule to identify new drug candidates for various diseases, particularly those related to enzyme dysregulation. In combination with advanced screening techniques, such as computational modeling and structure-activity relationship studies, this compound could lead to the discovery of novel therapeutic agents that target previously untapped biological pathways.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, non-natural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
