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13-Iodo-2,5,8,11-tetraoxatridecane

  CAS No.: 143127-81-5   Cat No.: BADC-01549   Purity: 98% +(stabilized with Copper chip) 4.5  

13-Iodo-2,5,8,11-tetraoxatridecane is a PEG-based halogenated ADC linker used for site-specific cysteine conjugation in antibody-drug conjugates, enhancing solubility, stability, and targeted drug delivery efficiency.

13-Iodo-2,5,8,11-tetraoxatridecane

Structure of 143127-81-5

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ADC Linker
Molecular Formula
C9H19IO4
Molecular Weight
318.15

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Synonyms
13-IODO-2,5,8,11-TETRAOXATRIDECANE; 2,5,8,11-Tetraoxatridecane, 13-iodo-; 1-[2-[2-(2-iodoethoxy)ethoxy]ethoxy]-2-methoxyethane
IUPAC Name
1-[2-[2-(2-iodoethoxy)ethoxy]ethoxy]-2-methoxyethane
Canonical SMILES
COCCOCCOCCOCCI
InChI
InChI=1S/C9H19IO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-9H2,1H3
InChIKey
KBOKJZSZVAHUPY-UHFFFAOYSA-N
Pictograms
Toxic; Health hazard
Signal Word
Danger

13-Iodo-2,5,8,11-tetraoxatridecane, a specialized chemical compound, finds applications across diverse scientific disciplines. Explore its key applications with elevated perplexity and burstiness:

Radiolabeling in Molecular Imaging: A pivotal role of 13-Iodo-2,5,8,11-tetraoxatridecane lies in molecular imaging, where it serves as a radiolabeling agent. By bonding with radioactive iodine isotopes, it enables real-time tracking of biological molecules within living organisms. This capability is indispensable in cancer research, enabling the visualization of tumor markers and the monitoring of targeted therapies' effectiveness.

Organic Synthesis: Within the realm of organic synthesis, this compound emerges as a versatile building block, especially prized for its role in crafting intricate molecules. Its distinct structure permits the incorporation of iodine atoms into larger organic frameworks, a quality highly valued in medicinal chemistry for forging innovative drug candidates.

Nanotechnology: Driving advancements in nanotechnology, 13-Iodo-2,5,8,11-tetraoxatridecane is harnessed for nanoparticle functionalization. It aids in anchoring nanoparticles onto diverse substrates or in crafting hybrid nanomaterials. This application bears significance for targeted drug delivery systems and the advancement of cutting-edge diagnostic tools, ushering in a new era of precision medicine.

Photochemistry: Stepping into the realm of photochemical reactions, this iodinated compound showcases its prowess as a photosensitive agent. When exposed to light, it triggers specific chemical transformations, offering valuable insights into light-induced processes. Its applications in photochemistry extend to the development of light-activated therapies and the exploration of materials science, paving the way for innovative solutions in various scientific domains.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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