Br-PEG4-NHBoc - CAS 1392499-32-9

Br-PEG4-NHBoc - CAS 1392499-32-9 Catalog number: BADC-00940

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Br-PEG4-NHBoc is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Category
ADCs Linker
Product Name
Br-PEG4-NHBoc
CAS
1392499-32-9
Catalog Number
BADC-00940
Molecular Formula
C15H30BrNO6
Molecular Weight
400.31
Br-PEG4-NHBoc

Ordering Information

Catalog Number Size Price Quantity
BADC-00940 -- $--
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Description
Br-PEG4-NHBoc is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Synonyms
t-Boc-N-amido-PEG4-bromide; Boc-NH-PEG4-Br; BocNH-PEG4-CH2CH2Br; N-Boc-PEG4-bromide; tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate; 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl (14-bromo-3,6,9,12-tetraoxatetradec-1-yl)carbamate; Carbamic acid, N-(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)-, 1,1-dimethylethyl ester
IUPAC Name
tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCOCCOCCBr
InChI
InChI=1S/C15H30BrNO6/c1-15(2,3)23-14(18)17-5-7-20-9-11-22-13-12-21-10-8-19-6-4-16/h4-13H2,1-3H3,(H,17,18)
InChIKey
KYOVSWOWVSWAII-UHFFFAOYSA-N
Density
1.223±0.06 g/cm3 (Predicted)
Solubility
Soluble in DCM, DMSO
LogP
2.36330
Appearance
Pale Yellow Oily Matter
Purity
≥95%
Shipping
Room temperature
Storage
Store at 2-8°C
Boiling Point
459.3±40.0°C (Predicted)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Br-PEG4-NHBoc
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