Br-PEG4-COOtBu - CAS 564476-32-0

Br-PEG4-COOtBu - CAS 564476-32-0 Catalog number: BADC-01136

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Br-PEG4-COOtBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Category
ADCs Linker
Product Name
Br-PEG4-COOtBu
CAS
564476-32-0
Catalog Number
BADC-01136
Molecular Formula
C15H29BrO6
Molecular Weight
385.29
Br-PEG4-COOtBu

Ordering Information

Catalog Number Size Price Quantity
BADC-01136 -- $--
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Description
Br-PEG4-COOtBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Synonyms
Bromo-PEG4-t-butyl ester; Br-PEG4-CH2CH2COOtBu; Bromo-PEG4-C2-Boc; 15-Bromo-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester; 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate; tert-butyl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate
IUPAC Name
tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCOCCBr
InChI
InChI=1S/C15H29BrO6/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h4-13H2,1-3H3
InChIKey
WLKHUFASPMJBHB-UHFFFAOYSA-N
Density
1.210±0.06 g/cm3 (Predicted)
Solubility
Soluble in DCM, DMF, DMSO
LogP
2.17950
PSA
63.22000
Appearance
Pale Yellow or Colorless Oily Matter
Purity
≥95%
Shipping
Room temperature
Storage
Store at 2-8°C
Boiling Point
415.8±35.0°C (Predicted)
Form
Solid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Azido-PEG3-PFP ester | Br-PEG4-COOtBu
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