mPEG9-amine - CAS 211859-73-3
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mPEG9-amine - CAS 211859-73-3 Catalog number: BADC-01067

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m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
mPEG9-amine
CAS
211859-73-3
Catalog Number
BADC-01067
Molecular Formula
C19H41NO9
Molecular Weight
427.53
Purity
≥95%
mPEG9-amine

Ordering Information

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BADC-01067 -- $-- Inquiry

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Description
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
m-PEG9-amine; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine; MPEG9-NH2; Methyl-PEG9-amine
IUPAC Name
2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI
InChI=1S/C19H41NO9/c1-21-4-5-23-8-9-25-12-13-27-16-17-29-19-18-28-15-14-26-11-10-24-7-6-22-3-2-20/h2-20H2,1H3
InChIKey
FYQAZBUDEOSOFG-UHFFFAOYSA-N
Density
1.060±0.06 g/cm3 (Predicted)
Solubility
Soluble in DMSO (10 mm)
LogP
0.42460
PSA
109.09000
Appearance
Pale Yellow Oily Liquid
Shelf Life
≥ 2 years
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C
Boiling Point
484.3±40.0 °C at 760 mmHg
Biological Activity
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
1.HDL functionality in South Asians as compared to white Caucasians.
Bakker LE1, Boon MR2, Annema W3, Dikkers A4, van Eyk HJ1, Verhoeven A5, Mayboroda OA5, Jukema JW6, Havekes LM7, Meinders AE1, Willems van Dijk K8, Jazet IM1, Tietge UJ3, Rensen PC9. Nutr Metab Cardiovasc Dis. 2016 Feb 19. pii: S0939-4753(15)30087-9. doi: 10.1016/j.numecd.2016.02.010. [Epub ahead of print]
BACKGROUND AND AIMS: South Asians have an exceptionally high risk of developing cardiovascular disease compared to white Caucasians. A contributing factor might be dysfunction of high density lipoprotein (HDL). We aimed to compare HDL function in different age groups of both ethnicities.
2.[Treatment of the old terrible triad of the elbow without operative history].
Zha YJ1, Jiang XY1, Gong MQ1. Beijing Da Xue Xue Bao. 2016 Apr 18;48(2):224-9.
OBJECTIVE: To introduce the surgical techniques and treating results of the old "terrible triad" of the elbow.
3.Impact of a systems engineering intervention on PMTCT service delivery in Côte d'Ivoire, Kenya, Mozambique: a cluster randomized trial.
Rustagi AS1, Gimbel S, Nduati R, Cuembelo MF, Wasserheit JN, Farquhar C, Gloyd S, Sherr K; with input from the SAIA Study Team. J Acquir Immune Defic Syndr. 2016 Apr 14. [Epub ahead of print]
BACKGROUND: Efficacious interventions to prevent mother-to-child HIV transmission (PMTCT) have not translated well into effective programs. Prior studies of systems engineering applications to PMTCT lacked comparison groups or randomization.
4.Comparison of mid-term haemodynamic performance between the BioValsalva and the BioIntegral valved conduits after aortic root replacement.
Wendt D1, Raweh A2, Knipp S2, El Gabry M2, Eißmann M3, Dohle DS2, Tsagakis K2, Thielmann M2, Jakob H2, Benedik J2. Interact Cardiovasc Thorac Surg. 2016 Apr 4. pii: ivw066. [Epub ahead of print]
OBJECTIVES: We retrospectively compared the haemodynamic performance of the BioValsalva (BV) and BioIntegral (BI) biological aortic-valved conduits in the aortic root position.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: mPEG9-amine
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