mPEG8-amine features a long PEG chain with an amine terminus, ideal for ADC linker synthesis. Its extended PEG8 spacer improves bioconjugate solubility, reduces aggregation, and enhances circulation stability in targeted drug delivery systems.
Structure of 869718-81-0
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Capabilities & Facilities
mPEG8-amine, a derivative of polyethylene glycol, boasts unique properties that make it a versatile choice for diverse biomedical and chemical applications. Explore four key applications of mPEG8-amine:
Drug Delivery: Powering the advancement of drug delivery systems, mPEG8-amine is instrumental in enhancing the solubility and stability of pharmaceutical compounds. Through the strategic conjugation of drugs with mPEG8-amine, researchers can extend their circulation time and mitigate immunogenicity, ultimately revolutionizing drug delivery efficiency and elevating therapeutic outcomes to new heights.
Bioconjugation: In the intricate domain of bioconjugation, mPEG8-amine emerges as a crucial player, facilitating the modification of proteins, peptides, and other biomolecules. Leveraging its amine functional group, mPEG8-amine enables stable covalent attachment to diverse targets, amplifying their solubility and biocompatibility. This crucial modification serves as a catalyst for enhancing the pharmacokinetics and efficacy of biologically active compounds.
Surface Modification: Delving into surface modification applications, mPEG8-amine takes center stage in the coating of medical devices and nanoparticles. By grafting mPEG8-amine onto surfaces, a hydrophilic layer is crafted, curbing protein adsorption and cell adhesion. This quality is pivotal in sculpting biocompatible surfaces that mitigate immune responses and optimize implant performance.
Diagnostics: Stepping into the realm of diagnostics, mPEG8-amine assumes a crucial role in steering the development of imaging agents and biosensors. The versatility of mPEG8-amine in conjugating with an array of probes or markers facilitates the creation of targeted diagnostics with exquisite specificity and sensitivity.
Catalog | Product Name | CAS | Inquiry |
---|---|---|---|
BADC-00938 | mPEG10-amine | 1383658-09-0 | |
BADC-00986 | mPEG7-amine | 170572-38-0 | |
BADC-01011 | mPEG6-amine | 184357-46-8 | |
BADC-01648 | m-PEG12-amine | 1977493-48-3 | |
BADC-01067 | mPEG9-amine | 211859-73-3 | |
BADC-01115 | mPEG2-amine | 31576-51-9 | |
BADC-01149 | mPEG3-amine | 74654-07-2 | |
BADC-01166 | mPEG4-amine | 85030-56-4 | |
BADC-01167 | mPEG11-amine | 854601-60-8 |
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