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C3-Amide-C4-NH2

  CAS No.: 65389-82-4   Cat No.: BADC-01685 4.5  

C3-Amide-C4-NH2 is an amide and amine-functionalized ADC linker intermediate offering flexible conjugation sites and improved payload stability in antibody-drug conjugates. Keywords: ADC linker, amide linker, amine group, payload conjugation, antibody-drug conjugate.

C3-Amide-C4-NH2

Structure of 65389-82-4

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ADC Linker
Molecular Formula
C8H18N2O
Molecular Weight
158.24

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Synonyms
N-butyrylputrescine
IUPAC Name
N-(4-aminobutyl)butanamide
Canonical SMILES
CCCC(=O)NCCCCN
InChI
InChI=1S/C8H18N2O/c1-2-5-8(11)10-7-4-3-6-9/h2-7,9H2,1H3,(H,10,11)
InChIKey
HQTYZWYSIZOPGA-UHFFFAOYSA-N

C3-Amide-C4-NH2 is a versatile chemical compound with various potential applications in bioscience. Here are some key applications of C3-Amide-C4-NH2:

Drug Development: C3-Amide-C4-NH2 can be utilized as an intermediate in the synthesis of pharmaceutical compounds. It is valuable in the formulation of drugs aimed at treating a wide range of conditions due to its structural properties. Researchers rely on such intermediates to develop novel therapeutic agents with improved efficacy and safety profiles.

Biochemical Research: In biochemical applications, C3-Amide-C4-NH2 serves as a vital reagent in the study of enzyme interactions and protein modifications. It can be used in assays to investigate the effects of amide modifications on protein function and stability. This knowledge is essential for understanding protein chemistry and developing enzyme inhibitors or activators.

Peptide Synthesis: C3-Amide-C4-NH2 is instrumental in the field of peptide synthesis, particularly for creating modified peptides with enhanced activity or stability. Its incorporation into peptide chains can improve binding affinity and selectivity toward targets. This application is crucial in the development of potent peptide-based drugs and diagnostic tools.

Molecular Probes: C3-Amide-C4-NH2 can be employed in designing molecular probes for imaging and diagnostic purposes. When conjugated with fluorescent or radioactive labels, it aids in visualizing and tracking biological molecules in cells and tissues. This helps researchers in studying dynamic biological processes and diagnosing diseases at the molecular level.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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