Name: H-D-Lys(N3)-OH
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Synonyms

6-Azido-D-norleucine; D-Azidonorleucine; H-D-Nle(6-N3)-OH; (R)-6-Azido-2-amino-hexanoic; D-Azidolysine; D-Anl; H-D-Lys(N3); H-D-Nle(N3)-OH; 6-Azido-D-lysine; N6-Diazo-D-lysine; (R)-2-Amino-6-azidohexanoic acid; N-epsilon-Azido-D-lysine; N-epsilon-Azido-D-norleucine; Nε-Azido-D-Lysine

IUPAC Name

(2R)-2-amino-6-azidohexanoic acid

Canonical SMILES

C(CCN=[N+]=[N-])C[C@H](C(=O)O)N

InChI

InChI=1S/C6H12N4O2/c7-5(6(11)12)3-1-2-4-9-10-8/h5H,1-4,7H2,(H,11,12)/t5-/m1/s1

InChIKey

HTFFMYRVHHNNBE-RXMQYKEDSA-N

Melting Point

166-172 °C

Appearance

White crystalline powder

Storage

Store at 2-8 °C

1. 1-Haloacylpiperazines

S Groszkowski, J Sienkiewicz, L Korzycka Pol J Pharmacol Pharm. 1975 Apr-Jun;27(2):183-6.

By direct acylation of piperazine with halogenocarboxylic acid chlorides in acid medium, the hydrochlorides of 1-haloacylpiperazines were obtained.

2. Metal-free and regiospecific synthesis of 3-arylindoles

Chuangchuang Xu, Wenlai Xie, Jiaxi Xu Org Biomol Chem. 2020 Apr 8;18(14):2661-2671. doi: 10.1039/d0ob00317d.

A convenient, metal-free, and organic acid-base promoted synthetic method to prepare 3-arylindoles from 3-aryloxirane-2-carbonitriles and arylhydrazine hydrochlorides has been developed. In the reaction, the organic acid catalyzes a tandem nucleophilic ring-opening reaction of aryloxiranecarbonitriles and arylhydrazine hydrochlorides and Fischer indolization. The organic base triethylamine plays a crucial role in the final elimination step in the Fischer indole synthesis, affording 3-arylindoles regiospecifically. The reaction features advantages of microwave acceleration, non-metal participation, short reaction time, organic acid-base co-catalysis, and broad substrate scope.