Fmoc-EDA-N3 - CAS 432507-62-5 Catalog number: BADC-01980

Fmoc-EDA-N3, also known as Fmoc-ethylenediamine-azide, is a versatile compound widely utilized in peptide synthesis and diverse biochemical applications. Here are the four key applications of Fmoc-EDA-N3:

Peptide Synthesis: A cornerstone in solid-phase peptide synthesis, Fmoc-EDA-N3 serves as a fundamental building block. The presence of its azide group allows for the targeted introduction of a myriad of functional groups through click chemistry. This feature proves invaluable in generating intricate and customized peptides essential for both research and therapeutic endeavors.

Bioconjugation: The multifaceted structure of Fmoc-EDA-N3 makes it a go-to choice for bioconjugation processes where peptides, proteins, and other biomolecules need to be linked. The azide group facilitates cycloaddition reactions with alkynes, facilitating the attachment of diverse moieties. This unique capability is instrumental in crafting bioconjugates tailored for applications such as targeted drug delivery, imaging, and diagnostics.

Surface Modification: Leveraging its properties, Fmoc-EDA-N3 finds application in surface modification techniques aimed at enhancing biomolecule adhesion and functionality. The azide moiety enables robust and stable click reactions with various alkyne-functionalized surfaces, a critical step in the development of biosensors, microarrays, and other advanced biotechnological devices.

Chemical Biology: Within the realm of chemical biology, Fmoc-EDA-N3 emerges as a potent tool for introducing azide functionality into target molecules, enabling subsequent modifications. This capability is particularly useful in labeling studies where azide-tagged molecules undergo further alteration with fluorescent probes. Such innovative techniques play a pivotal role in visualizing and monitoring intricate biological processes at the molecular level.