(2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent.
Catalog Number | Size | Price | Quantity |
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BADC-01896 | -- | $-- |
(2S,4S)-H-L-Pro(4-N3)-OH hydrochloride, a proline derivative commonly utilized in biochemical research and drug development, serves as a cornerstone in various applications explored with high perplexity and burstiness.
Peptide Synthesis: Serving as a fundamental component in peptide and peptidomimetic synthesis, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride's azide group allows for versatile functionalization via click chemistry, facilitating in-depth studies of protein-protein interactions. Researchers harness this compound to craft precise peptide sequences tailored for diverse biochemical assays, unlocking new avenues in peptide-based research.
Protein Labeling: The exceptional azide functionality of (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride plays a crucial role in bioorthogonal chemistry for protein labeling. Incorporating the azide-modified proline into peptides enables scientists to attach fluorescent dyes or other probes through click reactions, enhancing investigations into protein dynamics and interactions within live cellular environments.
Drug Development: With its potential in designing novel drug candidates, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride, featuring the azide group, opens avenues for creating proline-rich peptidomimetics with enhanced pharmacokinetic properties. Researchers can evaluate the biological activity of these compounds to unveil promising therapeutic agents, heralding advancements in drug discovery and development.
Structural Biology: Enriching studies in structural biology, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride finds application in NMR and crystallographic research. Incorporation of this proline derivative into peptides aids in structural determination by providing specific labeling sites, facilitating the elucidation of three-dimensional protein structures and complexes. This knowledge is pivotal in deciphering protein function and strategizing targeted interventions for therapeutic purposes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.