(2S,4S)-H-L-Pro(4-N3)-OH hydrochloride

(2S,4S)-H-L-Pro(4-N3)-OH hydrochloride Catalog number: BADC-01896

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(2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent.

Category
ADCs Linker
Product Name
(2S,4S)-H-L-Pro(4-N3)-OH hydrochloride
Catalog Number
BADC-01896
Molecular Formula
C5H9ClN4O2
Molecular Weight
192.60

Ordering Information

Catalog Number Size Price Quantity
BADC-01896 -- $--
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Description
(2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent.
IUPAC Name
(2S,4S)-4-azidopyrrolidine-2-carboxylic acid;hydrochloride
Canonical SMILES
C1C(CNC1C(=O)O)N=[N+]=[N-].Cl
InChI
InChI=1S/C5H8N4O2.ClH/c6-9-8-3-1-4(5(10)11)7-2-3;/h3-4,7H,1-2H2,(H,10,11);1H/t3-,4-;/m0./s1
InChIKey
BVURXEMVHARMIF-MMALYQPHSA-N

(2S,4S)-H-L-Pro(4-N3)-OH hydrochloride, a proline derivative commonly utilized in biochemical research and drug development, serves as a cornerstone in various applications explored with high perplexity and burstiness.

Peptide Synthesis: Serving as a fundamental component in peptide and peptidomimetic synthesis, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride's azide group allows for versatile functionalization via click chemistry, facilitating in-depth studies of protein-protein interactions. Researchers harness this compound to craft precise peptide sequences tailored for diverse biochemical assays, unlocking new avenues in peptide-based research.

Protein Labeling: The exceptional azide functionality of (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride plays a crucial role in bioorthogonal chemistry for protein labeling. Incorporating the azide-modified proline into peptides enables scientists to attach fluorescent dyes or other probes through click reactions, enhancing investigations into protein dynamics and interactions within live cellular environments.

Drug Development: With its potential in designing novel drug candidates, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride, featuring the azide group, opens avenues for creating proline-rich peptidomimetics with enhanced pharmacokinetic properties. Researchers can evaluate the biological activity of these compounds to unveil promising therapeutic agents, heralding advancements in drug discovery and development.

Structural Biology: Enriching studies in structural biology, (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride finds application in NMR and crystallographic research. Incorporation of this proline derivative into peptides aids in structural determination by providing specific labeling sites, facilitating the elucidation of three-dimensional protein structures and complexes. This knowledge is pivotal in deciphering protein function and strategizing targeted interventions for therapeutic purposes.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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