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Protected derivative for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for click reactions.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01971 | -- | $-- | Inquiry |
(2S,3R)-(Fmoc-amino)-3-azidobutyric acid, a specialized amino acid derivative, plays a crucial role in peptide synthesis and bioconjugation applications. Here are four key applications presented with a high degree of perplexity and burstiness:
Solid-Phase Peptide Synthesis: In the realm of solid-phase peptide synthesis (SPPS), this compound stands out for its capacity to introduce azido-functional groups into peptides. The Fmoc protection group, with its ability for selective reactions, enables the incremental assembly of intricate peptides. This functionality facilitates the fabrication of peptides with distinct chemical properties, which are pivotal for both research endeavors and therapeutic applications.
Click Chemistry: Harnessing the azido group within (2S,3R)-3-azidobutyric acid, click chemistry emerges as a powerful tool for linking the peptide to various alkyne-containing molecules. This technique allows for the conjugation of peptides to drugs, fluorescent markers, or other proteins, expanding the versatility of synthesized peptides. Particularly advantageous in target-specific drug delivery and imaging applications, click chemistry opens up new avenues for innovation in biomedicine.
Bioorthogonal Labeling: A cornerstone in bioorthogonal labeling methodologies, this compound facilitates the incorporation of non-native chemical functionalities into biological molecules without disrupting natural biochemical processes. By leveraging (2S,3R)-(Fmoc-amino)-3-azidobutyric acid, researchers can label and track biomolecules within living cells with minimal interference. This approach is indispensable for investigating dynamic biological processes and complex interactions within cellular environments.
Orthogonal Protection Strategies: (2S,3R)-(Fmoc-amino)-3-azidobutyric acid plays a pivotal role in orthogonal protection strategies within intricate peptide synthesis. Its Fmoc protection group can be selectively removed from other protective units, enabling multi-step synthesis with exceptional precision. This strategic approach is essential for crafting highly functionalized peptides and proteins, essential for biochemical research endeavors and therapeutic advancements.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
