Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-01386 | PROTAC BRD4 Degrader-9 | 2417370-42-2 |
| PROTAC BRD4 Degrader-9 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. It can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50 values of 0.86 nM and 7.6 nM, respectively. | Inquiry | |
| BADC-01388 | PROTAC BRD4 Degrader-10 | 2417370-49-9 |
| PROTAC BRD4 Degrader-10, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 1.3 and 18 nM, respectively. | Inquiry | |
| BADC-01390 | PROTAC BRD4 Degrader-13 | 2417370-71-7 |
| PROTAC BRD4 Degrader-13, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.025 and 6.0 nM, respectively. | Inquiry | |
| BADC-01387 | PROTAC BRD4 Degrader-12 | 2417370-90-0 |
| PROTAC BRD4 Degrader-12, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.39 and 0.24 nM, respectively. | Inquiry | |
| BADC-01381 | Taltobulin hydrochloride | |
| Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic tripeptide cysteine analog, Taltobulin is a potent antimicrotubule that circumvents P-glycoprotein-mediated drug resistance in vitro and in vivo sex. Taltobulin hydrochloride inhibits purified tubulin polymerization, disrupts microtubule organization in cells, and induces mitotic arrest and apoptosis. | Inquiry | |
| BADC-01384 | Aminohexylgeldanamycin hydrochloride | 1146534-45-3 |
| Aminohexylgeldanamycin (AHGDM) hydrochloride, a derivative of Geldanamycin, is a heat shock protein 90 (HSP90) inhibitor. Aminohexylgeldanamycin hydrochloride has anti-angiogenic and anti-tumor activities. | Inquiry | |
| BADC-01382 | Fmoc-MMAE | 474645-26-6 |
| Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE) and a potent tubulin inhibitor. | Inquiry | |
| BADC-01352 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | 2166376-51-6 |
| Glucocorticoid receptor agonist-1 Ala Ala Mal is a glucocorticoid that is also an agonist of the glucocorticoid receptor. The glucocorticoid receptor agonist-1Ala Ala Mal can be used to prepare ADC. | Inquiry | |
| BADC-01356 | SC209 | 1977557-86-0 |
| SC209 is an ADC cytotoxic used to synthesize anti-EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002. | Inquiry | |
| BADC-01357 | PNU-159682 carboxylic acid | 1204819-92-0 |
| PNU-159682 carboxylic acid (compound 53) is a potent ADC cytotoxin encoding a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid is involved in protein folding and diverse functions such as cell adhesion, cell signaling, glycoprotein turnover, and roles in inflammation and immune responses. | Inquiry | |
| BADC-01358 | DMEA-PNU-159682 | 1799421-48-9 |
| DMEA-PNU-159682 (molecule D12) is an ADC cytotoxic molecule consisting of neomycin metabolite (MMDX) from liver microsomes and the potent ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-01359 | Anticancer agent 81 | |
| Anticancer agent 81 can induce DNA damage and lead to tumor cell cycle arrest and apoptosis. It is used as a payload to conjugate with trastuzumab to obtain the antibody-drug conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of trastuzumab. | Inquiry | |
| BADC-01363 | Dideoxy-amanitin | 58255-46-2 |
| Dideoxy-amanitin is an α-Amanitin derivative. α-Amanitin is an extremely toxic bicyclic octapeptide isolated from the death-cap mushroom, Amanita phalloides. As a potent inhibitor of RNA polymerase II, α-amanitin is toxic to eukaryotic cells. | Inquiry | |
| BADC-01364 | TAM470 | 1802498-63-0 |
| TAM470 is an ADC cytolysin, inhibiting tubulin polymerization and depolymerization. TAM470 can be used in the synthesis of OMTX705 that is a novel FAP-targeting ADC demonstrates activity in chemotherapy and pembrolizumab-resistant solid tumor models. | Inquiry | |
| BADC-01366 | Gly-Cyclopropane-Exatecan | 2414254-49-0 |
| Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. | Inquiry | |
| BADC-01368 | NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT | 2857037-69-3 |
| NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a toxin payload in antibody drug conjugates that can inhibit topoisomerase I, and has good ADC activity in vivo and in vitro. | Inquiry | |
| BADC-01370 | Azonafide-PEABA | |
| Azonafide-PEABA is a cytotoxic drug. | Inquiry | |
| BADC-01372 | INX-SM-6 | 2734878-16-9 |
| INX-SM-6 is a cytotoxic that can be used for targeted anti-inflammatory agent. INX-SM-6 inhibits human PBMCS producting LPS-induced IL-1β. | Inquiry | |
| BADC-01373 | Corixetan | 1952359-26-0 |
| Corixetan is an efficient chelator with thorium. | Inquiry | |
| BADC-01375 | CC-885-CH2-PEG1-NH-CH3 | 2722698-03-3 |
| CC-885-CH2-PEG1-NH-CH3 is a neoDegrader used in Antibody neoDegrader Conjugate (AnDC). | Inquiry |
