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Taltobulin hydrochloride

  CAS No.:   Cat No.: BADC-01381   Purity: 98.34% 4.5  

Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic tripeptide cysteine analog, Taltobulin is a potent antimicrotubule that circumvents P-glycoprotein-mediated drug resistance in vitro and in vivo sex. Taltobulin hydrochloride inhibits purified tubulin polymerization, disrupts microtubule organization in cells, and induces mitotic arrest and apoptosis.

Taltobulin hydrochloride

Structure of

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Category
ADC Cytotoxin
Molecular Formula
C27H44ClN3O4
Molecular Weight
510.11
Shipping
Store at 0-4°C for short term (days to weeks) or -20°C for long term (months to years), away from moisture

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
HTI-286 hydrochloride; SPA-110 hydrochloride
IUPAC Name
(E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid;hydrochloride
Canonical SMILES
CC(C)C(C=C(C)C(=O)O)N(C)C(=O)C(C(C)(C)C)NC(=O)C(C(C)(C)C1=CC=CC=C1)NC.Cl
InChI
InChI=1S/C27H43N3O4.ClH/c1-17(2)20(16-18(3)25(33)34)30(10)24(32)22(26(4,5)6)29-23(31)21(28-9)27(7,8)19-14-12-11-13-15-19;/h11-17,20-22,28H,1-10H3,(H,29,31)(H,33,34);1H/b18-16+;/t20-,21-,22-;/m1./s1
InChIKey
UBHYRJPUQWUXCX-LPWSJWOVSA-N
Appearance
Solid
Storage
Store at 0-4°C for short term (days to weeks) or -20°C for long term (months to years), away from moisture

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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