Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00773 | Thailanstatin D | |
| a Pre-mRNA splicing inhibitor. The direct precursor of Thailanstatin A. Thailanstatin D is used as a cytotoxin for ADCs. | Inquiry | |
| BADC-00774 | Fr901463 | |
| a potent cell cycle inhibitor. Fr901463 exhibited potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. | Inquiry | |
| BADC-00777 | Meayamycin | |
| a potent pre-mRNA splicing inhibitor. Meayamycin modulates or inhibits splicing by targeting SF3B1. | Inquiry | |
| BADC-00779 | Pladienolide D | |
| a potent pre-mRNA splicing inhibitor. Pladienolide D has shown strong antitumor activity via targeting SF3b. | Inquiry | |
| BADC-00781 | Spliceostatin B | |
| a potent pre-mRNA splicing inhibitor. Spliceostatin B, an analog of FR901464, shows a weaker cytotoxic effect in cancer cells than FR901464. | Inquiry | |
| BADC-00782 | Spliceostatin C | |
| a potent pre-mRNA splicing inhibitor. Spliceostatin C is an analog of the natural product FR901464 and has shown a potent inhibit activity of eukaryotic RNA splicing via binding to SF3b. | Inquiry | |
| BADC-00783 | Sudemycin C | |
| a potent pre-mRNA splicing inhibitor. Sudemycin C has a potent inhibit activity of eukaryotic RNA splicing via binding to SF3b. | Inquiry | |
| BADC-00785 | Sudemycin E | 1197054-49-1 |
| a potent pre-mRNA splicing inhibitor. Sudemycin E is an analog of the natural product FR901464 and show a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00786 | Sudemycin E0 | |
| a potent pre-mRNA splicing inhibitor. Sudemycin E0 is an analog of the natural product FR901464 and shows a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00787 | Sudemycin F1 | |
| a potent pre-mRNA splicing inhibitor. Sudemycin F1 is an analog of the natural product FR901464 and shows a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00793 | PDM3 | |
| 20-O-Deme-thylansamitocin P-3 (PDM3),an ansamacrolide and maytansine analogue, has a greater antitumor activities against P388 and L 1210 than AP3. | Inquiry | |
| BADC-00794 | Esperamicin | |
| Esperamicinis an antitumor antibiotics, which combines the structural features of the anthracyclines and the enediynes. Esperamicinis are extremely toxic DNA splicing compounds and exhibits highly potent antitumor activity. | Inquiry | |
| BADC-00795 | Anthramcyin | |
| Anthramycin is a class of Pyrrolobenzodiazepines (PBDs)that shows antibacterial and potent antitumor activity. Anthramycin works by selectively inhibiting the synthesis of RNA and DNA of carcinoma cells. | Inquiry | |
| BADC-00824 | Luisol A | 225110-59-8 |
| Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, anthraquinone antibiotic analog, is an ADC Cytotoxin. | Inquiry | |
| BADC-00829 | Diacetyl Agrochelin | 247115-75-9 |
| Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines. | Inquiry | |
| BADC-00835 | DC4SMe | 615538-47-1 |
| DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC) for targeted therapy of tumors. | Inquiry | |
| BADC-00836 | DC4 | 615538-48-2 |
| DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors. | Inquiry | |
| BADC-00799 | Streptonigrin | 3930-19-6 |
| Bruneomycin is a benzoquinone antibiotic produced by Auiw-myces albus van bruneomycini and Act. echinatus. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity. It has inhibitory effect on lymphosarcoma Lio-1, lymphocytic leukemia NK/L1 and L-5178, Ehrlich ascites carcinoma, sarcoma-180, and has inhibitory effect on sarcoma-37 invalid. | Inquiry | |
| BADC-01385 | DC10SMe | |
| DC10SMe is a DNA alkylating agent useful in the synthesis of antibody drug conjugates (ADCs). DC10SMe has IC50 values of 15 pM, 12 pM and 12 pM against Ramos, Namalwa and HL60/s cancer cells, respectively. | Inquiry | |
| BADC-01389 | PROTAC BRD4 Degrader-11 | |
| PROTAC BRD4 Degrader-11 is a PROTAC linked by ligands for von Hippel-Lindau and BRD4. It is conjugated with STEAP1 and CLL1 antibodies to degrade BRD4 protein in PC3 prostate cancer cells with DC50s of 0.23 nM and 0.38 nM, respectively. | Inquiry |
