Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00795 | Anthramcyin | |
| Anthramycin is a class of Pyrrolobenzodiazepines (PBDs)that shows antibacterial and potent antitumor activity. Anthramycin works by selectively inhibiting the synthesis of RNA and DNA of carcinoma cells. | Inquiry | |
| BADC-00797 | Distamycin A | 636-47-5 |
| It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture. | Inquiry | |
| BADC-00799 | Streptonigrin | 3930-19-6 |
| Bruneomycin is a benzoquinone antibiotic produced by Auiw-myces albus van bruneomycini and Act. echinatus. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity. It has inhibitory effect on lymphosarcoma Lio-1, lymphocytic leukemia NK/L1 and L-5178, Ehrlich ascites carcinoma, sarcoma-180, and has inhibitory effect on sarcoma-37 invalid. | Inquiry | |
| BADC-00801 | Epirubicin | 56420-45-2 |
| Epirubicin, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. It is clinically active against a broad range of tumor types, including breast cancer, malignant lymphomas, soft tissue sarcomas, lung cancer, pleural mesothelioma, gastrointestinal cancer, head and neck cancer, ovarian cancer, prostatic carcinoma, transitional bladder carcinoma and so on. | Inquiry | |
| BADC-00814 | DC44SMe | 1354787-76-0 |
| DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC) for the targeted treatment of cancer.. | Inquiry | |
| BADC-00824 | Luisol A | 225110-59-8 |
| Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, anthraquinone antibiotic analog, is an ADC Cytotoxin. | Inquiry | |
| BADC-00829 | Diacetyl Agrochelin | 247115-75-9 |
| Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines. | Inquiry | |
| BADC-00835 | DC4SMe | 615538-47-1 |
| DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC) for targeted therapy of tumors. | Inquiry | |
| BADC-00836 | DC4 | 615538-48-2 |
| DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors. | Inquiry | |
| BADC-01347 | Trastuzumab-MC-MMAE | |
| Trastuzumab-mc-MMAE is an ADC product consisting of an anti-HER2 antibody (Trastuzumab) conjugated to MMAE via an Mc linker. It has been used to treat breast, ovarian and lung cancer by depolymerizing microtubule MOA (mechanism of action). | Inquiry | |
| BADC-01352 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | 2166376-51-6 |
| Glucocorticoid receptor agonist-1 Ala Ala Mal is a glucocorticoid that is also an agonist of the glucocorticoid receptor. The glucocorticoid receptor agonist-1Ala Ala Mal can be used to prepare ADC. | Inquiry | |
| BADC-01356 | SC209 | 1977557-86-0 |
| SC209 is an ADC cytotoxic used to synthesize anti-EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002. | Inquiry | |
| BADC-01357 | PNU-159682 carboxylic acid | 1204819-92-0 |
| PNU-159682 carboxylic acid (compound 53) is a potent ADC cytotoxin encoding a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid is involved in protein folding and diverse functions such as cell adhesion, cell signaling, glycoprotein turnover, and roles in inflammation and immune responses. | Inquiry | |
| BADC-01358 | DMEA-PNU-159682 | 1799421-48-9 |
| DMEA-PNU-159682 (molecule D12) is an ADC cytotoxic molecule consisting of neomycin metabolite (MMDX) from liver microsomes and the potent ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-01359 | Anticancer agent 81 | |
| Anticancer agent 81 can induce DNA damage and lead to tumor cell cycle arrest and apoptosis. It is used as a payload to conjugate with trastuzumab to obtain the antibody-drug conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of trastuzumab. | Inquiry | |
| BADC-01362 | BAY 1135626 | 1404071-37-9 |
| BAY 1135626 is used to synthesize BAY 1129980. BAY 1129980 (C4.4A-ADC) is a promising therapeutic candidate for the treatment of NSCLC and other cancers expressing C4.4A. | Inquiry | |
| BADC-01363 | Dideoxy-amanitin | 58255-46-2 |
| Dideoxy-amanitin is an α-Amanitin derivative. α-Amanitin is an extremely toxic bicyclic octapeptide isolated from the death-cap mushroom, Amanita phalloides. As a potent inhibitor of RNA polymerase II, α-amanitin is toxic to eukaryotic cells. | Inquiry | |
| BADC-01364 | TAM470 | 1802498-63-0 |
| TAM470 is an ADC cytolysin, inhibiting tubulin polymerization and depolymerization. TAM470 can be used in the synthesis of OMTX705 that is a novel FAP-targeting ADC demonstrates activity in chemotherapy and pembrolizumab-resistant solid tumor models. | Inquiry | |
| BADC-01365 | S-Me-DM4 | 890654-03-2 |
| S-Me-DM4 is an ADC cytotoxin molecule. It inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. | Inquiry | |
| BADC-01366 | Gly-Cyclopropane-Exatecan | 2414254-49-0 |
| Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. | Inquiry |
