Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00310 | MMAD hydrochloride | 173441-26-4 |
| Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. | Inquiry | |
| BADC-00312 | Q Bu-i | |
| Q Bu-i is a potent ADC cytotoxin payload that targets microtubule dynamics, inducing apoptosis in cancer cells. Its application in antibody-drug conjugates facilitates targeted tumor eradication with minimized off-target effects. | Inquiry | |
| BADC-00313 | Q Pr | |
| Q Pr functions as a microtubule inhibitor ADC payload with high cytotoxicity, disrupting mitotic spindle formation in cancer cells. Incorporated in antibody-drug conjugates, Q Pr improves selectivity and potency in targeted therapies. | Inquiry | |
| BADC-00315 | Quireston-A | |
| Quireston-A is an effective ADC cytotoxin payload with DNA-damaging activity, used in antibody-drug conjugates for precise cancer cell targeting. Its mechanism involves inducing apoptosis via DNA crosslinking, optimizing ADC therapeutic efficacy in solid tumors and hematologic malignancies. | Inquiry | |
| BADC-00322 | [Tyr2] Scyllatoxin | |
| [Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. Synthetic, originally from Leiurus quinquestriatus hebraeus scorpion venom. A blocker of Apamin-sensitive Ca2+-activated K+ channels. | Inquiry | |
| BADC-00323 | Sevedindione | |
| Sevedindione is a selective ADC cytotoxin used as an ADC payload with strong DNA-interacting properties. It enables precise delivery of cytotoxic agents in antibody-drug conjugates, boosting tumor cell eradication while minimizing systemic toxicity. Applications include targeted cancer therapeutics. | Inquiry | |
| BADC-00327 | Idarubicin | 58957-92-9 |
| Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. | Inquiry | |
| BADC-00331 | Seco-DuocarmycinDME | |
| Seco-DuocarmycinDME is a highly effective ADC cytotoxin payload causing DNA alkylation and apoptosis. It is used in antibody-drug conjugates to improve targeted cancer therapy outcomes. | Inquiry | |
| BADC-00332 | Seco-DuocarmycinCN | 1613286-54-6 |
| Seco-DuocarmycinCN serves as a selective ADC payload with DNA-alkylating activity, facilitating tumor cell apoptosis. It enhances ADC specificity and potency in targeted therapies. | Inquiry | |
| BADC-00333 | Seco-DuocarmycinDMG | 1613286-55-7 |
| Seco-DuocarmycinDMG is a potent ADC cytotoxin payload designed for antibody-drug conjugates, inducing DNA damage and cell death. It improves therapeutic efficacy and precision in cancer treatments. | Inquiry | |
| BADC-00334 | Seco-DuocarmycinDMA | |
| Seco-DuocarmycinDMA is an ADC payload with strong DNA alkylation properties, enhancing tumor-selective cytotoxicity in antibody-drug conjugates. It supports precision oncology through effective payload delivery. | Inquiry | |
| BADC-00336 | Seco-Duocamycin GA | 1613286-59-1 |
| Seco-Duocamycin GA is a highly cytotoxic ADC payload causing DNA damage, used in antibody-drug conjugates for selective tumor targeting. It boosts ADC therapeutic index and efficacy. | Inquiry | |
| BADC-00338 | Auristatin T | 1799603-53-4 |
| Auristatin T is a highly potent ADC cytotoxin payload that inhibits microtubule polymerization, disrupting cancer cell division. It enhances antibody-drug conjugate efficacy in targeted cancer therapies by inducing apoptosis in proliferating tumor cells, suitable for both hematologic and solid tumor ADC designs. | Inquiry | |
| BADC-00344 | Ducamycin Analog | 372954-15-9 |
| Ducamycin Analog is a DNA-alkylating ADC payload that enhances tumor cell killing in antibody-drug conjugates. As a potent ADC cytotoxin, it supports precision oncology applications through selective cytotoxicity. | Inquiry | |
| BADC-00345 | Tubulysin B | 205304-87-6 |
| Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. | Inquiry | |
| BADC-00362 | Duocarmycin B1 | 124325-93-5 |
| It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. | Inquiry | |
| BADC-00569 | Cryptophycin 1 | 124689-65-2 |
| Cryptophycin 1, produced by Nostoc sp. GSV 224, is a potent cytotoxic anti-microtubule agent. Cryptophycin 1 can induce cell apoptosis, and has anti-tumor activity and excellent anti-proliferation ability. | Inquiry | |
| BADC-00593 | Apaziquone | 141304-51-0 |
| Apaziquone is an indolequinone bioreductive prodrug and analog of mitomycin C with potential antineoplastic and radiosensitization activities. Apaziquone is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death. | Inquiry | |
| BADC-00715 | Boc-Val-Dil-Dap-OH | 1415246-54-6 |
| Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
| BADC-00716 | Boc-Val-Dil-Dap-Phe-OMe | |
| Boc-Val-Dil-Dap-Phe-OMe is a specialized ADC payload designed for precise cleavage and release in tumor microenvironments, enhancing antibody-drug conjugate cytotoxicity and selectivity for targeted cancer therapy. | Inquiry |
