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Sevedindione

  CAS No.:   Cat No.: BADC-00323   Purity: 95 % (TLC). 4.5  

Sevedindione is a selective ADC cytotoxin used as an ADC payload with strong DNA-interacting properties. It enables precise delivery of cytotoxic agents in antibody-drug conjugates, boosting tumor cell eradication while minimizing systemic toxicity. Applications include targeted cancer therapeutics.

Sevedindione

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Category
ADC Cytotoxin
Molecular Formula
C27H41NO3
Molecular Weight
427.62
Shipping
Room temperature, or blue ice upon request.
Shipping
Store at +4 °C, in dark place.

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
Sevedindione; Prestwick_183; CHEMBL4759213; (1S,2R,6R,10R,14R,15R,18S,23R)-14-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-dione
IUPAC Name
(1S,2R,6R,10R,14R,15R,18S,23R)-14-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-dione
Canonical SMILES
CC1CCC2C(C3CCC4(C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(=O)C6)C)O)C
InChI
InChI=1S/C27H41NO3/c1-15-4-5-24-16(2)18-7-9-27(31)20(19(18)14-28(24)13-15)11-21-22(27)12-25(30)23-10-17(29)6-8-26(21,23)3/h15-16,18-24,31H,4-14H2,1-3H3/t15-,16-,18?,19-,20+,21?,22-,23-,24?,26-,27+/m1/s1
InChIKey
QIIPLDGFOSWORQ-FQEDYCFASA-N
Solubility
Well in ethanol and chloroform
Melting Point
215-217 °C.
Appearance
Solid powder
Shipping
Room temperature, or blue ice upon request.
Storage
Store at +4 °C, in dark place.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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