Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00088 | Nemorubicin | 108852-90-0 |
| Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. | Inquiry | |
| BADC-00153 | Chlorotoxin | 163515-35-3 |
| Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chlorotoxin binds to Cl- channels (small conductance epithelial chloride channels) in the brain and spinal cord and inhibits Cl- influx. | Inquiry | |
| BADC-00182 | Duocarmycin analog | |
| Duocarmycin analog has cytotoxicity for solid tumor cells that can be used for antibody-drug conjugates (ADCs). Duocarmycins and the analogs acts via binding to the minor groove of DNA and alkylating the nucleobase adenine at the N3 position, which leads to DNA damage and cancer cell death. | Inquiry | |
| BADC-00253 | Luteolin 7-O-glucoside | 5373-11-5 |
| Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin. | Inquiry | |
| BADC-00266 | Galantamine hydrobromide | 1953-04-4 |
| Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. | Inquiry | |
| BADC-00290 | Lycorine hydrochloride | 2188-68-3 |
| Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. | Inquiry | |
| BADC-00330 | Irofulven | 158440-71-2 |
| Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. | Inquiry | |
| BADC-00335 | DC-1 | |
| DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00343 | Seco-Duocarmycin MB | |
| Seco-Duocarmycin MB is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00346 | Maytansine | 35846-53-8 |
| Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. | Inquiry | |
| BADC-00360 | Tubulysin M | 936691-46-2 |
| Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00361 | Combretastatin A4 | 117048-59-6 |
| Combretastatin A4 is a stilbenoid isolated from Combretum caffrum. Combretastatin A4 was shown to inhibit tubulin polymerization (IC50 = 2.2 μM). It has demonstrable antineoplastic activity. | Inquiry | |
| BADC-00775 | FR-901464 | 146478-72-0 |
| It is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. | Inquiry | |
| BADC-00790 | Mithramycin A | 18378-89-7 |
| Mithramycin A is an antineoplastic antibiotic produced by Streptomyces plicatus. Mithramycin A is a polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA. | Inquiry | |
| BADC-00791 | Illudin S | 1149-99-1 |
| Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. | Inquiry | |
| BADC-00798 | Actinomycin D | 50-76-0 |
| Actinomycin D is a chromopeptide antineoplastic antibiotic that exhibits high antibacterial and antitumor activity. Actinomycin D binds to single- and double-stranded DNA and subsequent inhibition of RNA and protein synthesis. | Inquiry | |
| BADC-00800 | Exatecan Mesylate | 169869-90-3 |
| Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. | Inquiry | |
| BADC-00001 | CBT-161 | |
| CBT-161 is an ADC that STI-A0602, the monoclonal antibody targeting c-Met, links tubulin inhibitors or DNA damaging agents via C-lock. Preclinical study showed that CBT-161 significantly inhibited tumor growth. | Inquiry | |
| BADC-00081 | Ungerine Nitrate | |
| Alkaloid , from plants of the Ungernia genus, Amaryllidaceae. | Inquiry | |
| BADC-00129 | Pentazolone hydrochloride | 21314-60-3 |
| Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine. | Inquiry |
