MC-VC-PABC - CAS 1703779-06-9

MC-VC-PABC - CAS 1703779-06-9 Catalog number: BADC-01494

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MC-VC-PABC is a potent and selective antibody-drug conjugate (ADC) used in the treatment of various cancers, including breast cancer, ovarian cancer, and non-small cell lung cancer. It combines the efficacy of a monoclonal antibody with the cytotoxicity of a potent chemotherapeutic agent, delivering targeted therapy directly to cancer cells while minimizing systemic side effects. MC-VC-PABC specifically targets cancer cells overexpressing certain antigens, making it a promising option for personalized cancer treatment.

Category
ADCs Linker
Product Name
MC-VC-PABC
CAS
1703779-06-9
Catalog Number
BADC-01494
Molecular Formula
C25H38N2O10
Molecular Weight
526.58
MC-VC-PABC

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BADC-01494 -- $--
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Description
MC-VC-PABC is a potent and selective antibody-drug conjugate (ADC) used in the treatment of various cancers, including breast cancer, ovarian cancer, and non-small cell lung cancer. It combines the efficacy of a monoclonal antibody with the cytotoxicity of a potent chemotherapeutic agent, delivering targeted therapy directly to cancer cells while minimizing systemic side effects. MC-VC-PABC specifically targets cancer cells overexpressing certain antigens, making it a promising option for personalized cancer treatment.
Synonyms
MC-VC-PABC-amide-PEG1-CH2-CC-885
IUPAC Name
[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[2-[2-[2-chloro-4-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methylcarbamoylamino]phenyl]ethoxy]ethyl]-N-methylcarbamate
Canonical SMILES
CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)N(C)CCOCCC2=C(C=C(C=C2)NC(=O)NCC3=CC4=C(C=C3)C(=O)N(C4)C5CCC(=O)NC5=O)Cl)NC(=O)CCCCCN6C(=O)C=CC6=O
InChI
InChI=1S/C55H68ClN11O13/c1-33(2)48(63-44(68)9-5-4-6-24-66-46(70)20-21-47(66)71)51(74)62-42(8-7-23-58-53(57)76)49(72)60-38-14-10-34(11-15-38)32-80-55(78)65(3)25-27-79-26-22-36-13-16-39(29-41(36)56)61-54(77)59-30-35-12-17-40-37(28-35)31-67(52(40)75)43-18-19-45(69)64-50(43)73/h10-17,20-21,28-29,33,42-43,48H,4-9,18-19,22-27,30-32H2,1-3H3,(H,60,72)(H,62,74)(H,63,68)(H3,57,58,76)(H2,59,61,77)(H,64,69,73)/t42-,43?,48-/m0/s1
InChIKey
SXHFPZWNOWBAQL-MPGWLFTNSA-N
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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