Mal-PEG2-bis-PEG3-BCN is a bi-functional maleimide ADC linker combining PEG spacers and BCN for click chemistry. It enhances antibody conjugation efficiency and payload stability in ADC synthesis for targeted cancer therapy.
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Capabilities & Facilities
Mal-PEG2-bis-PEG3-BCN, a versatile bioconjugation reagent extensively utilized in biochemical and medical research.
Protein and Antibody Conjugation: An essential tool for scientists, Mal-PEG2-bis-PEG3-BCN facilitates the modification and conjugation of proteins and antibodies. Its maleimide group selectively reacts with thiol groups in cysteine residues, enabling precise biomolecule attachment. This conjugation method is pivotal in creating antibody-drug conjugates and other biotherapeutics, enhancing their stability and efficacy in combating diseases.
Nanoparticle Functionalization: Delving into the nanoscale realm, Mal-PEG2-bis-PEG3-BCN is harnessed for nanoparticle functionalization. By enhancing solubility and biocompatibility through its PEG linker, this compound provides nanoparticles with a hydrophilic surface, minimizing non-specific interactions in biological environments.
Hydrogel Formation: The PEG chains within this reagent bestow hydrogels with customizable swelling properties and mechanical strength, essential for supporting cell encapsulation and controlled release of therapeutic agents.
Catalog | Product Name | CAS | Inquiry |
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BADC-00442 | Mal-PEG6-NHS | 1137109-21-7 | |
BADC-00448 | Mal-PEG-NHS | 1260092-50-9 | |
BADC-00443 | Mal-PEG5-NHS | 1315355-92-0 | |
BADC-00450 | Mal-PEG4-NHS | 1325208-25-0 | |
BADC-01679 | Mal-PEG2-Val-Cit-PABA-PNP | 1345681-52-8 | |
BADC-00936 | Mal-PEG2-acid | 1374666-32-6 | |
BADC-00449 | Mal-PEG4-PFP | 1415800-42-8 | |
BADC-00453 | Mal-PEG2-NHS ester | 1433997-01-3 | |
BADC-00603 | Mal-PEG3-NHS ester | 1537892-36-6 | |
BADC-00966 | Mal-PEG4-VC-PAB-DMEA | 1569261-93-3 |
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