Name: 1-N-Boc-3-hydroxyazetidine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

1-Boc-3-hydroxyazetidine; N-Boc-3-hydroxyazetidine; 1-(tert-Butoxycarbonyl)-3-hydroxyazetidine; 3-Hydroxy-azetidine-1-carboxylic acid tert-butyl ester

IUPAC Name

tert-butyl 3-hydroxyazetidine-1-carboxylate

Canonical SMILES

CC(C)(C)OC(=O)N1CC(C1)O

InChI

InChI=1S/C8H15NO3/c1-8(2,3)12-7(11)9-4-6(10)5-9/h6,10H,4-5H2,1-3H3

InChIKey

XRRXRQJQQKMFBC-UHFFFAOYSA-N

Density

1.184±0.06 g/cm3

Melting Point

36-43°C

Storage

Keep in dark place, Sealed in dry, Room Temperature

Signal Word

Danger

Boiling Point

253.7±33.0 °C at 760 mmHg

1-N-Boc-3-hydroxyazetidine, a pivotal compound in organic synthesis, boasts diverse applications in scientific research and industry. Here are four key applications presented with high perplexity and burstiness:

Pharmaceutical Synthesis: Serving as a crucial intermediate, 1-N-Boc-3-hydroxyazetidine plays a prominent role in pharmaceutical compound synthesis. Its distinctive structure, featuring both a Boc-protected amine and a hydroxy group, enables the intricate construction of complex molecules. This inherent versatility is instrumental in the creation of novel drugs and the optimization of synthetic pathways, propelling innovation in the realm of pharmaceuticals.

Peptide Synthesis: Within the domain of peptide synthesis, 1-N-Boc-3-hydroxyazetidine acts as a foundational building block for the production of innovative amino acid derivatives. Integrating this compound into peptide sequences can result in the generation of peptides endowed with heightened stability and enhanced biological activity. This application is essential for the synthesis of peptides with therapeutic relevance, driving advancements in the field of peptide-based therapeutics.

Material Science: The utilization of 1-N-Boc-3-hydroxyazetidine in material science is particularly noteworthy, contributing to the development of cutting-edge polymers and materials. Its capacity to form stable, functionalized structures renders it ideal for crafting advanced materials tailored to specific properties. This capability finds application in diverse fields such as drug delivery systems and the creation of environmentally friendly, biodegradable plastics, showcasing the versatility of this compound in material design.

Medicinal Chemistry: In the realm of medicinal chemistry, 1-N-Boc-3-hydroxyazetidine serves as a pivotal tool for exploring structure-activity relationships (SAR) in drug discovery endeavors. By judiciously modifying this compound, researchers can curate a diverse library of analogs to pinpoint potent and selective drug candidates. This strategic approach expedites the discovery and development of novel therapeutic agents, driving forward innovation in the domain of medicinal chemistry.