1,6-Bis(mesyloxy)hexane - CAS 4239-24-1

1,6-Bis(mesyloxy)hexane - CAS 4239-24-1 Catalog number: BADC-01526

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1,6-Bis(mesyloxy)hexane is a compound widely used in the biomedical field. It plays an extremely important role as an important intermediate in the synthesis of various pharmacological preparations and medicinal substances.

Category
ADCs Linker
Product Name
1,6-Bis(mesyloxy)hexane
CAS
4239-24-1
Catalog Number
BADC-01526
Molecular Formula
C8H18O6S2
Molecular Weight
274.35
1,6-Bis(mesyloxy)hexane

Ordering Information

Catalog Number Size Price Quantity
BADC-01526 -- $-- Inquiry
Description
1,6-Bis(mesyloxy)hexane is a compound widely used in the biomedical field. It plays an extremely important role as an important intermediate in the synthesis of various pharmacological preparations and medicinal substances.
Synonyms
1,6-Hexanediol, dimethanesulfonate; 1,6-Bis(mesyloxy)hexane; 6-methylsulfonyloxyhexyl methanesulfonate; hexane-1,6-diyl dimethanesulfonate; Hexasulphan; Hexasulfan; Hexane dimethanesulphonate
IUPAC Name
6-methylsulfonyloxyhexyl methanesulfonate
Canonical SMILES
CS(=O)(=O)OCCCCCCOS(=O)(=O)C
InChI
InChI=1S/C8H18O6S2/c1-15(9,10)13-7-5-3-4-6-8-14-16(2,11)12/h3-8H2,1-2H3
InChIKey
WZOJEWBBWCYINS-UHFFFAOYSA-N

1,6-Bis(mesyloxy)hexane, a multifunctional molecule utilized in organic synthesis and pharmaceutical research, boasts diverse applications. Below are four key applications presented with a high degree of perplexity and burstiness:

Cross-Linking Agents: Embracing its role as a cross-linking agent in polymer chemistry, 1,6-Bis(mesyloxy)hexane fosters the establishment of interconnections between polymer chains. This fosters the production of materials with heightened mechanical and thermal attributes. Such cross-linked polymers serve in various domains including coatings, adhesives, and the creation of biocompatible materials, amplifying their utility across industries.

Synthesis of Macrocycles: Stepping into the realm of drug development, this compound plays a pivotal role in synthesizing macrocyclic compounds. By facilitating the linkage of reactive functional groups, 1,6-Bis(mesyloxy)hexane aids in the formation of intricate ring structures crucial for selectively interacting with biological targets. This function is paramount in crafting potent and selective pharmaceutical agents, driving advancements in therapeutic innovation.

Chemical Linkers in Bioconjugation: Within bioconjugation methodologies, 1,6-Bis(mesyloxy)hexane assumes the role of a chemical linker, bridging diverse biomolecules such as peptides and proteins. This linkage is indispensable for sculpting targeted drug delivery systems and diagnostic tools. By fortifying molecular bonds, it elevates the efficacy and specificity of biomedical applications, paving the path for precise and tailored medical interventions.

Modification of Clinical Drugs: Delving into pharmaceutical realms, 1,6-Bis(mesyloxy)hexane emerges as a transformative tool for modifying existing drugs by introducing mesylate groups to boost solubility and reactivity. This strategic alteration enables the development of drug derivatives endowed with enhanced pharmacokinetic profiles. By finetuning these modifications, researchers can optimize therapeutic outcomes while mitigating adverse effects, heralding a new era of refined pharmacological solutions.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: 1,6-Bis(mesyloxy)hexane
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