Pladienolide D

Pladienolide D Catalog number: BADC-00779

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a potent pre-mRNA splicing inhibitor. Pladienolide D has shown strong antitumor activity via targeting SF3b.

Category
ADCs Cytotoxin
Product Name
Pladienolide D
Catalog Number
BADC-00779
Molecular Formula
C30H48O9
Molecular Weight
552.71
Pladienolide D

Ordering Information

Catalog Number Size Price Quantity
BADC-00779 -- $--
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Description
a potent pre-mRNA splicing inhibitor. Pladienolide D has shown strong antitumor activity via targeting SF3b.
Synonyms
(8E,12E,14E)-7-acetoxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide; (8E,12E,14E)-7-acetoxy-6,10,12,16,20-pentamethyl-3,6,16,21-tetrahydroxy-18,19-epoxytricosa-8,12,14-trien-11-olide; (8E,12E,14E)-7-acetoxy-6,3,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide; (E)-8-Acetoxy-12-[(1E,3E)-7,8-epoxy-5,10-dihydroxy-1,5,9-trimethyl-1,3-dodecadiene-1-yl]-4,7-dihydroxy-7,11-dimethyl-1-oxa-9-cyclododecen-2-one
Canonical SMILES
CCC(C(C)C1C(O1)CC(C)(C=CC=C(C)C2C(C=CC(C(CCC(CC(=O)O2)O)(C)O)OC(=O)C)C)O)O
InChI
InChI=1S/C30H48O9/c1-8-23(33)20(4)28-24(38-28)17-29(6,35)14-9-10-18(2)27-19(3)11-12-25(37-21(5)31)30(7,36)15-13-22(32)16-26(34)39-27/h9-12,14,19-20,22-25,27-28,32-33,35-36H,8,13,15-17H2,1-7H3/b12-11+,14-9+,18-10+
InChIKey
SDUSVHUQNWGNCQ-RRJBRJTHSA-N
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Room temperature
Storage
-20°C
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Pladienolide D
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