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N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide

  CAS No.: 1226050-10-7   Cat No.: BADC-00546 4.5  

N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide is an aldehyde ADC linker featuring chlorophenoxy functionality, ideal for site-specific antibody conjugation and enhanced stability in ADC drug delivery systems.

N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide

Structure of 1226050-10-7

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ADC Linker
Molecular Formula
C16H14ClNO3
Molecular Weight
303.74
Shipping
Room temperature

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IUPAC Name
N-[2-(4-chlorophenoxy)ethyl]-4-formylbenzamide
Canonical SMILES
C1=CC(=CC=C1C=O)C(=O)NCCOC2=CC=C(C=C2)Cl
InChI
InChI=1S/C16H14ClNO3/c17-14-5-7-15(8-6-14)21-10-9-18-16(20)13-3-1-12(11-19)2-4-13/h1-8,11H,9-10H2,(H,18,20)
InChIKey
UWTPCMAIFMAPIG-UHFFFAOYSA-N
Shipping
Room temperature

N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide is a compound of significant interest in the field of medicinal chemistry due to its potential pharmacological applications. This molecule’s structure, featuring a benzamide moiety linked to a chlorophenoxy ethyl group and a formyl functional group, grants it unique properties that can be exploited in various therapeutic areas. Its primary application has been observed in the development of pharmaceuticals aimed at treating inflammation-related conditions. The chlorophenoxy group is known to contribute to the compound's ability to modulate biological pathways associated with inflammatory responses, offering a promising template for designing drugs with enhanced efficacy and reduced side effects.

Moreover, N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide has demonstrated potential as an intermediary in synthesizing more complex organic compounds. Its formyl group provides a reactive site conducive to further chemical modifications, enabling chemists to develop new derivatives with specialized properties for diverse applications. For instance, by participating in reactions such as reductive amination or aldol condensation, this compound can be transformed into a variety of bioactive molecules. These derivatives can serve as participants in drug discovery processes, particularly in lead optimization stages where structural modifications are essential for improving pharmacokinetic and pharmacodynamic profiles.

Beyond pharmaceuticals, this compound finds applications in agricultural chemistry, particularly as a herbicide or fungicide precursor. The structural features of N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide allow it to interact with specific biological targets in plants and fungi, disrupting their growth and survival. Its efficacy as part of pest control formulations offers an intriguing alternative to conventional agrochemicals, providing pathways for the development of safer, more targeted pest management strategies. This capability not only helps in maintaining crop health but also contributes to sustainable agricultural practices by minimizing collateral damage to non-target organisms and the environment.

In addition to these direct applications, the study of N-(2-(4-Chlorophenoxy)ethyl)-4-Formylbenzamide also serves an educational purpose. It allows researchers and students in organic and medicinal chemistry to explore complex organic synthesis pathways and understand structure-activity relationships (SAR). By analyzing how modifications to this compound's structure affect its biological activity, learners gain insights into the principles of drug design and development, thereby enhancing their capacity to innovate future therapeutic agents. Such knowledge is critical in academia and industry, fostering a generation of chemists equipped with the tools to address emerging challenges in healthcare and environmental stewardship.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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