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Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01286 | -- | $-- | Inquiry |
Methyltetrazine-Maleimide is a versatile chemical compound widely used in bioconjugation strategies due to its specific reactivity and stability. Here are some key applications of Methyltetrazine-Maleimide:
Protein Labeling: Methyltetrazine-Maleimide is highly effective for the site-specific labeling of proteins. Its use in click chemistry conjugation techniques allows researchers to attach fluorescent dyes or other molecules to proteins without altering their natural function. This capability is crucial for studying protein dynamics and interactions in real-time assays.
Drug Delivery: In drug delivery systems, Methyltetrazine-Maleimide is employed to create stable linkages between therapeutic agents and carrier molecules. This ensures precise targeting and release of drugs at the desired site within the body. By improving the efficiency and specificity of drug delivery, this application holds potential for enhancing treatment outcomes in diseases like cancer.
Biosensor Development: Methyltetrazine-Maleimide plays a critical role in the development of biosensors, where it facilitates the assembly of stable and specific detection platforms. The compound's reactivity can be used to immobilize biomolecules on sensor surfaces, enabling the detection of various analytes with high sensitivity and specificity.
Immunoassays: In immunoassays, Methyltetrazine-Maleimide is used to conjugate antibodies with enzymes, fluorophores, or other signal-producing labels. This enhances the detection capabilities of assays, allowing for the identification of specific antigens in complex samples. These conjugations support a wide range of applications, from diagnostic testing to research in immunology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
