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Methyltetrazine-Maleimide

  CAS No.:   Cat No.: BADC-01286   Purity: 98.0% 4.5  

Methyltetrazine-Maleimide is a heterobifunctional ADC linker combining maleimide and methyltetrazine groups. It enables site-specific conjugation via thiol-maleimide chemistry and rapid bioorthogonal click reactions for optimized antibody-drug conjugate assembly.

Methyltetrazine-Maleimide

Structure of

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ADC Linker
Molecular Formula
C17H16N6O3
Molecular Weight
352.35
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Solubility
10 mm in DMSO
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

Methyltetrazine-Maleimide is a versatile chemical compound widely used in bioconjugation strategies due to its specific reactivity and stability. Here are some key applications of Methyltetrazine-Maleimide:

Protein Labeling: Methyltetrazine-Maleimide is highly effective for the site-specific labeling of proteins. Its use in click chemistry conjugation techniques allows researchers to attach fluorescent dyes or other molecules to proteins without altering their natural function. This capability is crucial for studying protein dynamics and interactions in real-time assays.

Drug Delivery: In drug delivery systems, Methyltetrazine-Maleimide is employed to create stable linkages between therapeutic agents and carrier molecules. This ensures precise targeting and release of drugs at the desired site within the body. By improving the efficiency and specificity of drug delivery, this application holds potential for enhancing treatment outcomes in diseases like cancer.

Biosensor Development: Methyltetrazine-Maleimide plays a critical role in the development of biosensors, where it facilitates the assembly of stable and specific detection platforms. The compound's reactivity can be used to immobilize biomolecules on sensor surfaces, enabling the detection of various analytes with high sensitivity and specificity.

Immunoassays: In immunoassays, Methyltetrazine-Maleimide is used to conjugate antibodies with enzymes, fluorophores, or other signal-producing labels. This enhances the detection capabilities of assays, allowing for the identification of specific antigens in complex samples. These conjugations support a wide range of applications, from diagnostic testing to research in immunology.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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