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MC-Ala-Ala-Asn-PAB is a linker extracted from patent CN104147612A, page 14. It can be used to synthesize the tumor microenvironment specific activated micromolecular targeted conjugate.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01692 | -- | $-- | Inquiry |
MC-Ala-Ala-Asn-PAB, a synthetic peptide with diverse applications in research and diagnostics, offers versatility and promise.
Enzyme Assays: At the forefront of enzyme research, MC-Ala-Ala-Asn-PAB serves as a pivotal substrate in enzyme assays, unraveling the intricacies of protease activity. By tracking the cleavage of this peptide by specific proteases, researchers unveil enzyme activity and specificity in quantifiable ways. This critical application not only elucidates enzyme kinetics but also facilitates the screening of potential enzyme inhibitors, propelling drug discovery efforts forward.
Diagnostic Tools: In the realm of diagnostics, MC-Ala-Ala-Asn-PAB emerges as a vital component in assays designed to probe the activity of disease-associated proteases. By gauging the cleavage of this peptide substrate, laboratories assess protease activity levels in biological samples, shedding light on disease states. This innovative approach proves particularly impactful in cancer diagnostics and monitoring treatment responses, steering medical interventions towards precision and efficacy.
Pharmacological Research: Central to pharmacological inquiries, MC-Ala-Ala-Asn-PAB is a cornerstone in exploring protease inhibition. By examining the interplay between this peptide and various inhibitor compounds, researchers pinpoint effective inhibitors with therapeutic potential. This strategic analysis aids in the development of drugs targeting proteases implicated in pathological conditions like cancer and inflammation, offering new avenues for treatment and management.
Biotechnological Applications: Venturing into biotechnology, MC-Ala-Ala-Asn-PAB emerges as a key player, demonstrating its adaptability in fusion proteins. By integrating this peptide sequence into recombinant proteins, scientists craft innovative constructs that can be selectively cleaved, enabling controlled activation or inactivation
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
