KetoABNO - CAS 7123-92-4

KetoABNO - CAS 7123-92-4 Catalog number: BADC-01582

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KetoABNO is a well-known antibody drug that strategically targets multiple cancer types prevalent in the biomedical field, such as breast, lung and colon cancer. This special compound can effectively avoid cancer-causing signaling pathways and perfectly prevent tumor expansion.

Category
ADCs Linker
Product Name
KetoABNO
CAS
7123-92-4
Catalog Number
BADC-01582
Molecular Formula
C8H12NO2
Molecular Weight
154.19
KetoABNO

Ordering Information

Catalog Number Size Price Quantity
BADC-01582 -- $-- Inquiry
Description
KetoABNO is a well-known antibody drug that strategically targets multiple cancer types prevalent in the biomedical field, such as breast, lung and colon cancer. This special compound can effectively avoid cancer-causing signaling pathways and perfectly prevent tumor expansion.
Synonyms
Norpseudopelleterine-N-oxyl; keto-ABNO; NPPN; 9-AZabicyclo[3.3.1]nonan-3-one N-oxyl
Canonical SMILES
C1CC2CC(=O)CC(C1)N2[O]
InChI
InChI=1S/C8H12NO2/c10-8-4-6-2-1-3-7(5-8)9(6)11/h6-7H,1-5H2
InChIKey
AMZBXNVXJGUYMF-UHFFFAOYSA-N
Melting Point
109-114°C
Appearance
Yellow Solid

KetoABNO is a synthetic small molecule that has been explored for its potential applications in chemical biology and drug discovery. It is a derivative of ABNO (Amino-phenylbutyl-1,3-dioxolane), a compound known for its ability to act as an electrophilic probe targeting specific enzymes or proteins in biological systems. The presence of a ketone functional group in KetoABNO enhances its reactivity, making it an effective tool for studying enzyme mechanisms, protein-protein interactions, and cellular signaling pathways. Researchers utilize KetoABNO to investigate the role of certain enzymes in disease processes and to identify novel therapeutic targets.

One of the key applications of KetoABNO is in the study of enzyme inhibition and the identification of potential drug candidates. By interacting with target enzymes, KetoABNO can be used to probe the active sites of these proteins, helping to elucidate their structures and functions. This is particularly valuable in the development of enzyme inhibitors for diseases where enzymatic activity plays a central role, such as in cancer, neurodegenerative disorders, or metabolic diseases. KetoABNO's ability to selectively bind and modulate enzyme activity makes it an important compound in the search for new, more effective therapeutics.

Another important application of KetoABNO is in the field of chemical proteomics, where it is used to identify and characterize proteins that interact with specific bioactive molecules. The electrophilic nature of KetoABNO allows it to covalently bind to nucleophilic sites on target proteins, which can then be isolated and identified through mass spectrometry or other proteomic techniques. This application is useful for mapping protein networks, understanding cellular signaling pathways, and identifying biomarkers for disease. By capturing protein interactions in vivo, KetoABNO contributes to a deeper understanding of complex biological systems and disease mechanisms.

KetoABNO is also being explored in the development of targeted therapies for diseases such as cancer and infectious diseases. By modifying its structure or conjugating it with other therapeutic agents, researchers aim to create compounds that selectively target disease-related proteins or cells. For example, KetoABNO can be linked to small molecule drugs, antibodies, or other therapeutic modalities to enhance the specificity and potency of treatment. This could improve the efficacy of therapies while reducing off-target effects, making it a valuable candidate for precision medicine.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: KetoABNO | Mal-PEG2-bis-PEG3-BCN
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