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CAS No.: 937188-59-5
Cat No.: BADC-01194
Purity: >98.0%
4.5 
Hydroxy-PEG4-propionic acid is a hydrophilic PEG linker featuring hydroxyl and carboxyl groups, facilitating dual reactivity in ADC linker design. It enables efficient conjugation and improves solubility and stability of antibody-drug conjugates in therapeutic applications.
Structure of 937188-59-5
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Hydroxy-PEG4-propionic acid, a versatile polyethylene glycol (PEG) derivative, finds extensive applications in various biomedical and pharmaceutical fields.
Drug Delivery: Employing Hydroxy-PEG4-propionic acid, scientists tailor the characteristics of drug molecules, augmenting their solubility, stability, and bioavailability. By conjugating this PEG derivative with drugs, it facilitates prolonged circulation time and diminishes immunogenicity.
Bioconjugation: In the domain of bioconjugation, Hydroxy-PEG4-propionic acid serves as a vital link between biomolecules like proteins, peptides, and antibodies. Through the process of PEGylation, solubility is enhanced, and aggregation of conjugated biomolecules is reduced, crucial for developing biopharmaceuticals with superior pharmacokinetics and minimal side effects.
Tissue Engineering: Leveraging Hydroxy-PEG4-propionic acid, researchers fashion hydrogels for applications in tissue engineering, fostering a conducive milieu for cell proliferation and tissue rejuvenation. By incorporating bioactive agents, such as growth factors, into the hydrogel matrix, it accelerates tissue repair and regeneration.
Diagnostic Imaging: Within the realm of diagnostic imaging, Hydroxy-PEG4-propionic acid plays a pivotal role in enhancing the properties of imaging agents. By conjugating imaging probes with this PEG derivative, solubility and biocompatibility of imaging agents are optimized, which translates to heightened imaging precision and accuracy.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-00926 | Hydroxy-PEG2-t-butyl ester | 133803-81-3 | |
| BADC-01015 | Hydroxy-PEG3-t-butyl ester | 186020-66-6 | |
| BADC-01684 | Hydroxy-PEG3-DBCO | 2566404-76-8 | |
| BADC-01130 | Hydroxy-PEG4-t-butyl ester | 518044-32-1 | |
| BADC-01137 | Hydroxy-PEG3-SS-PEG3-alcohol | 5662-81-7 | |
| BADC-01158 | Hydroxy-PEG10-t-butyl ester | 778596-26-2 | |
| BADC-01187 | Hydroxy-PEG1-acid | 89211-34-7 |
Hydroxy-PEG4-propionic acid
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Hydroxy-PEG4-propionic acid
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