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Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01194 | -- | $-- | Inquiry |
Hydroxy-PEG4-propionic acid, a versatile polyethylene glycol (PEG) derivative, finds extensive applications in various biomedical and pharmaceutical fields.
Drug Delivery: Employing Hydroxy-PEG4-propionic acid, scientists tailor the characteristics of drug molecules, augmenting their solubility, stability, and bioavailability. By conjugating this PEG derivative with drugs, it facilitates prolonged circulation time and diminishes immunogenicity.
Bioconjugation: In the domain of bioconjugation, Hydroxy-PEG4-propionic acid serves as a vital link between biomolecules like proteins, peptides, and antibodies. Through the process of PEGylation, solubility is enhanced, and aggregation of conjugated biomolecules is reduced, crucial for developing biopharmaceuticals with superior pharmacokinetics and minimal side effects.
Tissue Engineering: Leveraging Hydroxy-PEG4-propionic acid, researchers fashion hydrogels for applications in tissue engineering, fostering a conducive milieu for cell proliferation and tissue rejuvenation. By incorporating bioactive agents, such as growth factors, into the hydrogel matrix, it accelerates tissue repair and regeneration.
Diagnostic Imaging: Within the realm of diagnostic imaging, Hydroxy-PEG4-propionic acid plays a pivotal role in enhancing the properties of imaging agents. By conjugating imaging probes with this PEG derivative, solubility and biocompatibility of imaging agents are optimized, which translates to heightened imaging precision and accuracy.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
