Hydroxy-PEG1-acid is a non-cleavable 1-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Catalog Number | Size | Price | Quantity | ||
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BADC-01187 | -- | $-- | Inquiry |
Hydroxy-PEG1-acid, a versatile compound highly valued in the bioscience industry for its exceptional properties, finds wide-ranging applications. Here are key applications of Hydroxy-PEG1-acid:
Drug Delivery: Harnessing the power of Hydroxy-PEG1-acid, researchers delve into enhancing the pharmacokinetics and stability of therapeutic agents. Through the strategic conjugation of drugs with PEG1-acid, solubility is amplified, and immunogenicity is curtailed, culminating in heightened bioavailability and prolonged circulation within the bloodstream.
Bioconjugation: In the intricate realm of protein and peptide chemistry, Hydroxy-PEG1-acid takes center stage in the process of PEGylation, wherein biomolecules undergo a metamorphosis. By affixing PEG chains to proteins or peptides, stability is bolstered, proteolytic degradation is subdued, and immunogenicity takes a back seat.
Biomolecular Probes: Delving into the realm of diagnostics and imaging, Hydroxy-PEG1-acid assumes a crucial role as a linker in the synthesis of biomolecular probes. These probes are meticulously crafted to hone in on specific biomarkers or cells, facilitating their discernment in diverse assays and imaging modalities. The innate flexibility and hydrophilicity endowed by PEG1-acid serve to elevate probe performance and precision, setting new benchmarks in probe technology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.