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Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01015 | -- | $-- | Inquiry |
Hydroxy-PEG3-t-butyl ester, a bifunctional polyethylene glycol derivative, finds diverse applications in both chemical and biological realms. Here are four key applications of Hydroxy-PEG3-t-butyl ester:
Drug Delivery Systems: In drug delivery systems, Hydroxy-PEG3-t-butyl ester facilitates the formulation of pharmaceutical compounds by enhancing their solubility and stability. By conjugating drugs with this PEG derivative, researchers can augment drug bioavailability and prolong circulation time within the body.
Bioconjugation: Serving as a versatile linker molecule for bioconjugation reactions, Hydroxy-PEG3-t-butyl ester enables the coupling of biomolecules like peptides, proteins, and antibodies. This conjugation not only bolsters the stability and solubility of biomolecules but also mitigates immunogenicity concerns.
Surface Modification: By enveloping surfaces with Hydroxy-PEG3-t-butyl ester, researchers can forge antifouling surfaces that hinder protein adsorption and cellular adhesion. This tailored modification proves exceedingly beneficial in the advancement of biosensors and implantable medical technologies.
Polymer Synthesis: Acting as a foundational element in polymer synthesis, Hydroxy-PEG3-t-butyl ester contributes to the creation of block copolymers and cutting-edge polymers. Its inclusion introduces specific functional groups that can be further tailored for diverse chemical applications. This innovative synthesis methodology enables the production of bespoke polymers with desired characteristics, shaping the landscape of materials science and nanotechnology with bespoke solutions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
