DSG Crosslinker - CAS 79642-50-5

DSG Crosslinker - CAS 79642-50-5 Catalog number: BADC-01162

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DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
DSG Crosslinker
CAS
79642-50-5
Catalog Number
BADC-01162
Molecular Formula
C13H14N2O8
Molecular Weight
326.26
DSG Crosslinker

Ordering Information

Catalog Number Size Price Quantity
BADC-01162 -- $--
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Description
DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Di(N-succinimidyl) glutarate; Bis(2,5-dioxopyrrolidin-1-yl) Pentanedioate
IUPAC Name
bis(2,5-dioxopyrrolidin-1-yl) pentanedioate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCCC(=O)ON2C(=O)CCC2=O
InChI
InChI=1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2
InChIKey
LNQHREYHFRFJAU-UHFFFAOYSA-N
Density
1.5±0.1 g/cm3
Solubility
10 mm in DMSO
Flash Point
247.2±31.5 °C
Index Of Refraction
1.572
LogP
-3.30
PSA
127.36000
Vapor Pressure
0.0±1.2 mmHg at 25°C
Biological Activity
DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Solid
Purity
99.3 %
Shipping
Room temperature
Storage
Store at -20 ℃, keep in dry and avoid sunlight.
Pictograms
Irritant
Signal Word
Warning
Boiling Point
485.1±55.0 °C at 760 mmHg
Form
Solid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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