Description
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
Synonyms
Di-tert-butyl iminodiacetate; tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate
IUPAC Name
tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate
Canonical SMILES
CC(C)(C)OC(=O)CNCC(=O)OC(C)(C)C
InChI
InChI=1S/C12H23NO4/c1-11(2,3)16-9(14)7-13-8-10(15)17-12(4,5)6/h13H,7-8H2,1-6H3
InChIKey
SMXMBXPLRFTROI-UHFFFAOYSA-N
Melting Point
38-42 ℃ (lit.)
Flash Point
134.0±23.2 °C
Index Of Refraction
1.446
Vapor Pressure
0.0±0.6 mmHg at 25°C
Appearance
White to tan powder, fiber or crystals
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 ℃, keep in dry and avoid sunlight.
Boiling Point
298 ℃ at 760 mmHg