Cyclooctyne-O-amido-PEG2-NHS ester - CAS 2101206-22-6

Cyclooctyne-O-amido-PEG2-NHS ester - CAS 2101206-22-6 Catalog number: BADC-01533

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Cyclooctyne-O-amido-PEG2-NHS ester is a highly versatile biomedical product extensively employed in the domains of bioconjugation and pharmaceutical transport. It showcases its adeptness as a reactive connector, thus expediting the conjugation of amine-infused entities with biomolecular components. Its cutting-edge composition exhibits remarkable utility in the realm of targeted pharmaceutical transport frameworks, antibody-drug conjugates, as well as bioimaging technologies, thereby augmenting the therapeutic approaches for an array of afflictions encompassing cancer and inflammatory disorders.

Category
ADCs Linker
Product Name
Cyclooctyne-O-amido-PEG2-NHS ester
CAS
2101206-22-6
Catalog Number
BADC-01533
Molecular Formula
C16H18N2Na2O14S2
Molecular Weight
572.42900
Cyclooctyne-O-amido-PEG2-NHS ester

Ordering Information

Catalog Number Size Price Quantity
BADC-01533 -- $--
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Description
Cyclooctyne-O-amido-PEG2-NHS ester is a highly versatile biomedical product extensively employed in the domains of bioconjugation and pharmaceutical transport. It showcases its adeptness as a reactive connector, thus expediting the conjugation of amine-infused entities with biomolecular components. Its cutting-edge composition exhibits remarkable utility in the realm of targeted pharmaceutical transport frameworks, antibody-drug conjugates, as well as bioimaging technologies, thereby augmenting the therapeutic approaches for an array of afflictions encompassing cancer and inflammatory disorders.
Synonyms
disodium,1-[8-(2,5-dioxo-3-sulfonatopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[(2-cyclooct-2-yn-1-yloxyacetyl)amino]ethoxy]ethoxy]propanoate
Canonical SMILES
C1CCC#CC(CC1)OCC(=O)NCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI
InChI=1S/C21H30N2O8/c24-18(16-30-17-6-4-2-1-3-5-7-17)22-11-13-29-15-14-28-12-10-21(27)31-23-19(25)8-9-20(23)26/h17H,1-4,6,8-16H2,(H,22,24)
InChIKey
PLHRQGJSIULEHT-UHFFFAOYSA-N
PSA
258.52000
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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