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Me-Tet-PEG5-COOH is an ADC linker containing 5 PEG units.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01859 | -- | $-- | Inquiry |
Me-Tet-PEG5-COOH, a versatile chemical compound serving as a linker or spacer in diverse biotechnological and biomedical applications, offers a plethora of possibilities.
Drug Delivery Systems: Me-Tet-PEG5-COOH plays a pivotal role as a linker, facilitating the conjugation of therapeutic molecules onto drug delivery carriers. By tethering drugs to the PEG-based linker, the pharmacokinetics and solubility of the drug can be enhanced, culminating in more effective delivery to targeted tissues. This mechanism significantly enhances therapeutic efficacy while concurrently mitigating the undesired side effects commonly associated with drug administration.
Protein Modification: Embracing PEGylation, a transformative process involving the attachment of polyethylene glycol (PEG) chains to proteins, Me-Tet-PEG5-COOH stands out for its ability to bolster protein stability and diminish immunogenic responses. Leveraging this compound can effectively prolong the circulation half-life of therapeutic proteins, ultimately amplifying their bioavailability and diminishing the necessity for frequent dosing.
Diagnostic Imaging: Me-Tet-PEG5-COOH emerges as a vital component in the conjugation of imaging agents to targeting molecules, heralding a paradigm shift in diagnostic imaging. By linking imaging agents to antibodies or ligands, precision targeting of disease sites is achieved, revolutionizing diagnostic accuracy. This sophisticated approach not only enhances the sensitivity and specificity of imaging techniques like MRI or PET scans but also promises unparalleled advancements in disease detection and monitoring.
Surface Modification: In the realm of biomaterials, Me-Tet-PEG5-COOH emerges as a game-changer, offering unparalleled surface modification capabilities that enhance biocompatibility and minimize non-specific adsorption. By grafting PEG chains onto surfaces, interactions with proteins and cells are attenuated, a critical facet in the development of advanced medical implants and biosensors. This innovative modification ensures optimal device performance within complex biological environments.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
