Cyclooctyne-O-amido-PEG4-NHS ester - CAS 2101206-50-0

Cyclooctyne-O-amido-PEG4-NHS ester - CAS 2101206-50-0 Catalog number: BADC-01531

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Cyclooctyne-O-amido-PEG4-NHS ester is a key reagent used in the biomedical industry for the efficient conjugation of biological molecules. It enables the site-specific modification of proteins, peptides, and antibodies for various applications such as drug delivery, diagnostics, and targeted therapy. This NHS ester derivative offers high stability and reactivity, making it suitable for the synthesis of bioconjugates used in the treatment of diseases like cancer and autoimmune disorders.

Category
ADCs Linker
Product Name
Cyclooctyne-O-amido-PEG4-NHS ester
CAS
2101206-50-0
Catalog Number
BADC-01531
Molecular Formula
C33H40N4O9S2
Molecular Weight
700.82
Cyclooctyne-O-amido-PEG4-NHS ester

Ordering Information

Catalog Number Size Price Quantity
BADC-01531 -- $--
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Description
Cyclooctyne-O-amido-PEG4-NHS ester is a key reagent used in the biomedical industry for the efficient conjugation of biological molecules. It enables the site-specific modification of proteins, peptides, and antibodies for various applications such as drug delivery, diagnostics, and targeted therapy. This NHS ester derivative offers high stability and reactivity, making it suitable for the synthesis of bioconjugates used in the treatment of diseases like cancer and autoimmune disorders.
Synonyms
Cyclooctyne-O-amido-PEG4-NHS ester
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[(2-cyclooct-2-yn-1-yloxyacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES
C1CCC#CC(CC1)OCC(=O)NCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI
InChI=1S/C25H38N2O10/c28-22(20-36-21-6-4-2-1-3-5-7-21)26-11-13-33-15-17-35-19-18-34-16-14-32-12-10-25(31)37-27-23(29)8-9-24(27)30/h21H,1-4,6,8-20H2,(H,26,28)
InChIKey
DXCWDXACHQRXMU-UHFFFAOYSA-N
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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