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Aminoethyl-SS-propionic acid

  CAS No.: 15579-00-7   Cat No.: BADC-00964   Purity: ≥95% 4.5  

Aminoethyl-SS-propionic acid is a disulfide-based cleavable linker ideal for constructing ADCs. Its thiol-sensitive bond enables selective intracellular drug release, making it suitable for redox-responsive bioconjugation and targeted delivery systems in oncology.

Aminoethyl-SS-propionic acid

Structure of 15579-00-7

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Category
ADC Linker
Molecular Formula
C5H11NO2S2
Molecular Weight
181.28
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
3-[(2-Aminoethyl)dithio]propionic Acid
IUPAC Name
Canonical SMILES
C(CSSCCN)C(=O)O
InChI
InChI=1S/C5H11NO2S2/c6-2-4-10-9-3-1-5(7)8/h1-4,6H2,(H,7,8)
InChIKey
HMMFDEBVQNRZLJ-UHFFFAOYSA-N
Density
1.32g/cm3
Solubility
10 mm in DMSO
Melting Point
138-141°C
Flash Point
159.1°C
Index Of Refraction
1.589
PSA
113.92000
Vapor Pressure
1.69E-05mmHg at 25°C
Appearance
Off-White to Beige Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
339.5°C at 760 mmHg
Form
Solid

Aminoethyl-SS-propionic acid is a versatile compound with wide-ranging applications across various scientific domains. Here are four key applications of Aminoethyl-SS-propionic acid, presented with a high degree of perplexity and burstiness:

Bioconjugation: A cornerstone of bioconjugation protocols, Aminoethyl-SS-propionic acid serves as a vital link between biomolecules such as proteins, peptides, and nucleic acids. Its inclusion enhances the solubility, stability, and functional attributes of the connected molecules, playing a pivotal role in advancing targeted drug delivery systems and diagnostic assays.

Drug Development: Within the realm of pharmaceutical research, Aminoethyl-SS-propionic acid emerges as a fundamental building block for synthesizing innovative drug candidates. Its unique chemical characteristics facilitate the creation of compounds with heightened efficacy and diminished side effects, offering a valuable resource for medicinal chemists engaged in the quest for novel therapeutic solutions.

Chemical Modification: The utilization of Aminoethyl-SS-propionic acid extends to the realm of surface and material chemical modification. Through its attachment to surfaces, researchers can forge functionalized materials endowed with specific binding properties, opening avenues for applications in biosensors, chromatography, and separation technologies. This breakthrough enables the creation of highly precise and sensitive analytical instruments.

Metabolic Engineering: In the domain of metabolic engineering, Aminoethyl-SS-propionic acid emerges as a potent tool for tinkering with metabolic pathways in microorganisms. By integrating this compound into metabolic pathways, researchers can amplify the production of desired metabolites or facilitate the synthesis of novel bioproducts. This process is pivotal for optimizing bioprocesses in industrial chemical, biofuel, and pharmaceutical production.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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